IS110: Lipid Lowering as an Anti-inflammatory Therapy on Vulnerable
Atherosclerotic Plaques
Masanori Aikawa, M.D., Ph.D.
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Figure 1. Potential
mechanisms involved in stabilizing atherosclerotic plaques in
the setting of lipid lowering. (LDL, low density lipoprotein;
ROS, reactive oxygen species; EC, endothelial cells; eNOS, endothelial
nitric oxide synthase; VCAM, vascular cell adhesion molecule;
MCP, monocyte chemoattractant; SMC, smooth muscle cell; MMP,
matrix metalloproteinase.) (Aikawa M. Potential Mechanisms of
Atheroscleroric Plaque Stabilization by Lipid Lowering. Cardiovascular
Risk Factors 1999; Vol. 9, No4. © Saned, S.L.) |
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