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IS110: Lipid Lowering as an Anti-inflammatory Therapy on Vulnerable Atherosclerotic Plaques
Masanori Aikawa, M.D., Ph.D.

Figure 1. Potential mechanisms involved in stabilizing atherosclerotic plaques in the setting of lipid lowering. (LDL, low density lipoprotein; ROS, reactive oxygen species; EC, endothelial cells; eNOS, endothelial nitric oxide synthase; VCAM, vascular cell adhesion molecule; MCP, monocyte chemoattractant; SMC, smooth muscle cell; MMP, matrix metalloproteinase.) (Aikawa M. Potential Mechanisms of Atheroscleroric Plaque Stabilization by Lipid Lowering. Cardiovascular Risk Factors 1999; Vol. 9, No4. © Saned, S.L.)


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