Japanese Circulation Society

IS058: Diabetes, PAI-1, and Atherogenesis
David J. Schneider, M.D.

Figure 2. Atherectomy specimens from diabetic and non-diabetic subjects showed increased immunoreactivity of PAI-1 in samples from diabetics, regardless of the type of diabetic treatment. This increase in PAI-1 was associated with a decrease in uPA.(Circulation 1998;97:2213-2221.)

Reprinted with permission from Lippincott Williams and Wilkins (www.lww.com).