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IS066 Keynote Lecture: Ischemic Preconditioning and Cardioprotection: Mechanisms by which Early (First Window) and Late (Second Window) Phases of Protection are Induced
James M. Downey, M.D.
Figure 4. Staurosporine, a blocker of PKC's kinase activity only blocks preconditioning's protection if given in the late protocol indicating that PKC is a mediator of protection. (Journal of Molecular and Cellular Cardiology 1997; 29:991-999.)

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