Plenary Session 6 New Alternative Therapies for Refractory Heart Failure
Seiji Takashima, Hiroshi Okamoto, Masafumi Yano,
Shinji Tomita
Figure 1. HB-EGF shedding
is inhibited and hypertrophic changes attenuated by KB-R7785
in the rat model of cardiac hypertrophy. Antibody 19 blocked
any effect by angiotensin II, endothelin-1 and phenylephrine,
showing this effect to be specific to HB-EGF.
