Vol.189 (2013.3.1) Impact Factor 2011 : 3.766  In 2012 (January to December), the average time for primary review for all original manuscripts submitted to Circulation Journal was 13.0 days. 新禁煙宣言2013 10年ぶりに更新しました（日本語版、英語版）。10年間のエビデンスを収載しています。 Circulation Journal Vol.77 No.3 目次 Circulation Journalの目次を掲載した JCS Newsletter目次号を配信しています。 オンラインジャーナルと合わせてご利用ください。

◆オンラインジャーナルはこちら◆

Message From the Editor-in-Chief

Circulation Journal Awards for the Year 2012
Hiroaki Shimokawa

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JCS Statement

Anti-Smoking Declaration 2013 – A Message From the Japanese Circulation Society –
The Anti-Smoking Promotion Committee of the Japanese Circulation Society

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Reviews

Fractional Flow Reserve to Guide Coronary Revascularization
Nico H.J. Pijls

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・561

Characteristics of Transient Receptor Potential Canonical Calcium-Permeable Channels and Their Relevance to Vascular Physiology and Disease
David J. Beech

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・570

Post-Infarction Inflammation and Left Ventricular Remodeling – A Double-Edged Sword –
Toshihisa Anzai

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・580

Intracoronary Imaging for Detecting Vulnerable Plaque
Kenichi Fujii, Hiroyuki Hao, Mitsumasa Ohyanagi, Tohru Masuyama

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・588

Editorials

Reconsideration of Anticoagulant Therapy in Japanese Patients With Atrial Fibrillation and Moderate Renal Impairment
Tsuyoshi Shiga

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Significance of Oscillatory Breathing on Cardiopulmonary Exercise Testing in Chronic Heart Failure
Shigeru Makita

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Coronary Vasospasm as an Underlying Etiology of Out-of-Hospital Cardiac Arrest
Yusuke Takagi

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Weight Change and Cardiovascular Mortality – Methodological Challenges –
Hiroshi Yatsuya, Frank B. Hu

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Nutrition as a New Treatment Target in Chronic Heart Failure
Miyuki Tsuchihashi-Makaya, Shintaro Kinugawa

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・604

Pregnancy-Related Acute Myocardial Infarction in Japan
Chizuko A. Kamiya

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Assessment of Longitudinal Myocardial Stiffness Is Not Enough to Evaluate Diastolic Function – What Is the Relevance of the Stiffness of Cardiomyocytes in the Transverse Direction? –
Martín Donato, Ricardo J. Gelpi

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Original Articles

Arrhythmia/Electrophysiology

Identification of High-Risk Brugada Syndrome Patients by Combined Analysis of Late Potential and T-Wave Amplitude Variability on Ambulatory Electrocardiograms
Koichiro Yoshioka, Mari Amino, Wojciech Zareba, Makiyoshi Shima, Atsushi Matsuzaki, Toshiharu Fujii, Shigetaka Kanda, Yoshiaki Deguchi, Yoshinori Kobayashi, Yuji Ikari, Itsuo Kodama, Teruhisa Tanabe

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Coronary Sinus Activation Pattern in the Differential Diagnosis of Regular Atrial Tachyarrhythmias During Catheter Ablation of Atrial Fibrillation
Ki-Hun Kim, Gi-Byoung Nam, Eun-Sun Jin, Dong-Kie Kim, Sang-Hoon Seol, Doo-Il Kim, HyungOh Choi, Yoo Ri Kim, Sung-Hwan Kim, Kee-Joon Choi, You-Ho Kim

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・619

Distribution of the Origin of Adenosine Triphosphate-Sensitive Atrial Tachycardias With the Earliest Activation Recorded in the His Bundle Catheter – Are They Limited to the Immediate Vicinity of the His bundle? –
Tomofumi Nakamura, Hitoshi Hachiya, Yasuaki Tanaka, Atsuhiko Yagishita, Koji Sugiyama, Masahito Suzuki, Mihoko Kawabata, Tetsuo Sasano, Kenzo Hirao, Mitsuaki Isobe

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Safety and Efficacy of Adjusted Dose of Rivaroxaban in Japanese Patients With Non-Valvular Atrial Fibrillation – Subanalysis of J-ROCKET AF for Patients With Moderate Renal Impairment –
Masatsugu Hori, Masayasu Matsumoto, Norio Tanahashi, Shin-ichi Momomura, Shinichiro Uchiyama, Shinya Goto, Tohru Izumi, Yukihiro Koretsune, Mariko Kajikawa, Masaharu Kato, Hitoshi Ueda, Kazuya Iwamoto, Masahiro Tajiri on behalf of the J-ROCKET AF study investigators

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Relationship Between CHADS2 Score and Efficacy of Antiarrhythmic Drug Therapy in Patients With Paroxysmal Atrial Fibrillation
Takashi Komatsu, Yoshihiro Sato, Mahito Ozawa, Fusanori Kunugita, Hironobu Ueda, Hideaki Tachibana, Yoshihiro Morino, Motoyuki Nakamura

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・639

Cardiovascular Intervention

Is Gender a Factor in the Reduction of Cardiovascular Risks With Exercise Training?
Noriteru Morita, Koichi Okita

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Qualitative and Quantitative Assessment of Stent Restenosis by Optical Coherence Tomography – Comparison Between Drug-Eluting and Bare-Metal Stents –
Ryoji Nagoshi, Toshiro Shinke, Hiromasa Otake, Junya Shite, Daisuke Matsumoto, Hiroyuki Kawamori, Masayuki Nakagawa, Amane Kozuki, Hirotoshi Hariki, Takumi Inoue, Tsuyoshi Ohsue, Yu Taniguchi, Masamichi Iwasaki, Ryo Nishio, Noritoshi Hiranuma, Akihide Konishi, Hiroto Kinutani, Naoki Miyoshi, Tomofumi Takaya, Shinichiro Yamada, Yoshinori Yasaka, Takatoshi Hayashi, Mitsuhiro Yokoyama, Hiroki Kato, Makoto Kadotani, Yoshio Ohnishi, Ken-ichi Hirata

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・652

Cardiac Rehabilitation

Relation Between Oscillatory Breathing and Cardiopulmonary Function During Exercise in Cardiac Patients
Jo Kato, Akira Koike, Masayo Hoshimoto-Iwamoto, Osamu Nagayama, Koji Sakurada, Akira Sato, Takeshi Yamashita, Karlman Wasserman, Kazutaka Aonuma

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・661

Cardiovascular Surgery

Usefulness of Cystatin C in the Postoperative Management of Pediatric Patients With Congenital Heart Disease
Akiko Yana, Satoshi Masutani, Takuro Kojima, Hirofumi Saiki, Mio Taketazu, Masanori Tamura, Hideaki Senzaki

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Critical Care

Characteristics of Patients With Cardiac Arrest Caused by Coronary Vasospasm
Nobuaki Kobayashi, Noritake Hata, Tetsuro Shimura, Shinya Yokoyama, Akihiro Shirakabe, Takuro Shinada, Kazunori Tomita, Daisuke Murakami, Masamichi Takano, Yoshihiko Seino, Hisashi Matsumoto, Kunihiro Mashiko, Kyoichi Mizuno

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・673

Epidemiology

Impact of Weight Change Since Age 20 and Cardiovascular Disease Mortality Risk – The Ohsaki Cohort Study –
Wan-Ting Chou, Masako Kakizaki, Yasutake Tomata, Masato Nagai, Yumi Sugawara, Shinichi Kuriyama, Ichiro Tsuji

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・679

Heart Failure

Prognostic Impact of Acute Kidney Injury in Patients With Acute Decompensated Heart Failure
Akihiro Shirakabe, Noritake Hata, Nobuaki Kobayashi, Takuro Shinada, Kazunori Tomita, Masafumi Tsurumi, Masato Matsushita, Hirokake Okazaki, Yoshiya Yamamoto, Shinya Yokoyama, Kuniya Asai, Kyoichi Mizuno

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Left Ventricular Diastolic Function Is Closely Associated With Mechanical Function of the Left Atrium in Patients With Paroxysmal Atrial Fibrillation
Jihei Sara Lee, Chi Young Shim, Jin Wi, Boyoung Joung, Jong-Won Ha, Moon Hyoung Lee, Hui-Nam Pak

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・697

Geriatric Nutritional Risk Index Predicts Functional Dependency and Mortality in Patients With Heart Failure With Preserved Ejection Fraction
Yoshiharu Kinugasa, Masahiko Kato, Shinobu Sugihara, Masayuki Hirai, Kensaku Yamada, Kiyotaka Yanagihara, Kazuhiro Yamamoto

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・705

Ischemic Heart Disease

Impact of Carotid Artery Ultrasound and Ankle-Brachial Index on Prediction of Severity of SYNTAX Score
Nobutaka Ikeda, Norihiro Kogame, Raisuke Iijima, Masato Nakamura, Kaoru Sugi

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Microsimulation for Clinical Decision-Making in Individual Patients With Established Coronary Artery Disease – A Concept –
Linda Battes, Isabella Kardys, Rogier Barendse, Ewout W. Steyerberg, Masoud Amiri, Marinus J.C.Eijkemans, Jaap W. Deckers, Douwe Postmus, Johanna J.M. Takkenberg, Ken Redekop, Eric Boersma

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・717

Pregnancy-Related Acute Myocardial Infarction in Japan – A Review of Epidemiology, Etiology and Treatment From Case Reports –
Hiroshi Satoh, Makoto Sano, Kenichiro Suwa, Masao Saotome, Tsuyoshi Urushida, Hideki Katoh, Hideharu Hayashi

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Metabolic Disorder

Sex Differences in the Associations of Testosterone and Sex Hormone-Binding Globulin With Metabolic Syndrome in Middle-Aged and Elderly Koreans – The Namwon Study –
Sun-Seog Kweon, Min-Ho Shin, Hae-Sung Nam, Seul-Ki Jeong, Kyeong-Soo Park, Jin-Su Choi, Young- Hoon Lee

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・734

Myocardial Disease

Increased Passive Stiffness of Cardiomyocytes in the Transverse Direction and Residual Actin and Myosin Cross-Bridge Formation in Hypertrophied Rat Hearts Induced by Chronic β-Adrenergic Stimulation
Wakako Sumita Yoshikawa, Kazufumi Nakamura, Daiji Miura, Juichiro Shimizu, Ken Hashimoto, Noriyuki Kataoka, Hiroko Toyota, Hiroshi Okuyama, Toru Miyoshi, Hiroshi Morita, Kengo Fukushima Kusano, Tatsuhito Matsuo, Miyako Takaki, Fumihiko Kajiya, Naoto Yagi, Tohru Ohe, Hiroshi Ito

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・741

Pediatric Cardiology and Adult Congenital Heart Disease

Psychosocial Factors Influencing Mental Health in Adults With Congenital Heart Disease
Junko Enomoto, Jun Nakazawa, Yoshiko Mizuno, Takeaki Shirai, Junko Ogawa, Koichiro Niwa

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・749

Pulmonary Circulation

Efficacy of Right Ventricular Free-Wall Longitudinal Speckle-Tracking Strain for Predicting Long-Term Outcome in Patients With Pulmonary Hypertension
Yoshiki Motoji, Hidekazu Tanaka, Yuko Fukuda, Keiko Ryo, Noriaki Emoto, Hiroya Kawai, Ken-ichi Hirata

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Valvular Heart Disease

Circulating Progenitor and Apoptotic Progenitor Cells in Patients With Aortic Regurgitation
Sara Shimoni, Iris Bar, Liaz Zilberman, Sorel Goland, Orly Edri, Gera Gandelman, Arnon Afek, Ari Shamiss, Jacob George

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・764

Vascular Biology and Vascular Medicine

Luteolin Inhibits Angiotensin II-Induced Human Umbilical Vein Endothelial Cell Proliferation and Migration Through Downregulation of Src and Akt Phosphorylation
Manyi Zhu, Dan Chen, Dongye Li, Hong Ding, Tian Zhang, Tongda Xu, Yanbin Zhang

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・772

High Leukocyte Count Is Associated With Peripheral Vascular Dysfunction in Individuals With Low Cardiovascular Risk
Jing Li, Andreas J. Flammer, Martin K. Reriani, Yoshiki Matsuo, Rajiv Gulati, Paul A. Friedman, Randal J. Thomas, Nicole P. Sandhu, Lilach O. Lerman, Amir Lerman

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・780

Images in Cardiovascular Medicine

Constrictive Pericarditis With Intrapericardial Abscess
Tomoya Hara, Hirotsugu Yamada, Akira Takashima, Hiromu Yamasaki, Kozue Ogasawara, Sachiko Bando, Takayuki Ise, Toshiyuki Niki, Kenya Kusunose, Yuka Ueda, Noriko Tomita, Koji Yamaguchi, Yoshio Taketani, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki, Hidehisa Horiguchi, Naomi Sakashita, Masataka Sata

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・786

JCS Guidelines

Guidelines for Diagnosis and Treatment of Aortic Aneurysm and Aortic Dissection (JCS 2011) – Digest Version –
JCS Joint Working Group

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Letters to the Editor

T-Wave Alternans and Heart Rate Turbulence in Patients After Myocardial In-farction
(Letter) John E. Madias

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(Reply) Kyoko Hoshida, Yosuke Miwa, Mutsumi Miyakoshi, Takehiro Tsukada, Satoru Yusu, Hideaki Yoshino, Takanori Ikeda

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・830

A Simple Homemade Carbon Dioxide Delivery System for Endovascular Procedures in the Iliofemoral Arteries
(Letter) Cynthia de Almeida Mendes, Nelson Wolosker, Mariana Krutman

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(Reply) Daizo Kawasaki

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■月刊誌 Circulation Journal Vol.77 No.3 広告掲載企業様一覧
「今日の治療指針」（株式会社医学書院）
クリアクター、コアテック、タンボコール、ニトロール、ワソラン（エーザイ株式会社）
サムスカ（大塚製薬株式会社）
プロサイリン、リピディル（科研製薬株式会社）
グルベス（キッセイ薬品工業株式会社）
スイニー（株式会社 三和化学研究所）
ダイアート（株式会社 三和化学研究所）
レザルタス（第一三共株式会社）
アイミクス（大日本住友製薬株式会社）
アジルバ（武田薬品工業株式会社）
循環器用製剤（トーアエイヨー株式会社）
ラナ1.5AG（日本化薬株式会社）
ミカムロ、ミカルディス（日本ベーリンガーインゲルハイム（株））
セララ（ファイザー株式会社）
VS-1500E、ＦＭ１９０（フクダ電子株式会社）
エパデール（持田製薬株式会社）
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