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Message From the Editor-in-Chief

Message From the Editor-in-Chief
Hiroaki Shimokawa

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Cardiovascular Epidemiology in Asia

Epidemiology of Heart Failure in Asia
Yasuhiko Sakata, Hiroaki Shimokawa

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Reviews

Biochemical and Physiological Regulation of Cardiac Myocyte Contraction by Cardiac-Specific Myosin Light Chain Kinase
Osamu Tsukamoto, Masafumi Kitakaze

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Epidemiology of Hypertension in Japan – Where Are We Now? –
Katsuyuki Miura, Masato Nagai, Takayoshi Ohkubo

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Do Minimally Invasive Approaches Improve Outcomes of Heart Valve Surgery?
Minoru Tabata, Toshihiro Fukui, Shuichiro Takanashi

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Editorials

Amiodarone-Related Sinoatrial Node Dysfunction and Its Implications in the Treatment of Atrial Fibrillation
Masaomi Chinushi

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Optimal International Normalized Ratio for Atrial Fibrillation in Asians and Japanese – Do We Really Know? –
Kang-Ling Wang, Chern-En Chiang

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Atrial Fibrillation After Cardiac Surgery
Akira Sezai, Motomi Shiono

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Direct Xa Inhibitors in Acute Coronary Syndrome
Masayasu Ikutomi, Fumitaka Nakamura

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Clinical Characteristics of Heart Failure With Preserved Ejection Fraction in Children
Masao Nakagawa

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Noninvasive and Accurate Evaluation of Cardiac Output in Patients With Pulmonary Hypertension
Kohtaro Abe

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Exercise Echocardiography in Asymptomatic or Minimally Symptomatic Chronic Severe Aortic Regurgitation – A New Era in the Search for ‘the Golden Moment’ for Surgery –
Kyung-Hee Kim, Hyung-Kwan Kim

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Original Articles

Arrhythmia/Electrophysiology

Chronic Amiodarone Therapy Impairs the Function of the Superior Sinoatrial Node in Patients With Atrial Fibrillation
Hee-Sun Mun, Changyu Shen, Hui-Nam Pak, Moon-Hyoung Lee, Shien-Fong Lin, Peng-Sheng Chen, Boyoung Joung

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Target International Normalized Ratio Values for Preventing Thromboembolic and Hemorrhagic Events in Japanese Patients With Non-Valvular Atrial Fibrillation – Results of the J-RHYTHM Registry –
Hiroshi Inoue, Ken Okumura, Hirotsugu Atarashi, Takeshi Yamashita, Hideki Origasa, Naoko Kumagai, Masayuki Sakurai, Yuichiro Kawamura, Isao Kubota, Kazuo Matsumoto, Yoshiaki Kaneko, Satoshi Ogawa, Yoshifusa Aizawa, Masaomi Chinushi, Itsuo Kodama, Eiichi Watanabe, Yukihiro Koretsune, Yuji Okuyama, Akihiko Shimizu, Osamu Igawa, Shigenobu Bando, Masahiko Fukatani, Tetsunori Saikawa, Akiko Chishaki on behalf of the J-RHYTHM Registry Investigators

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Repeated Catheter Ablation of Atrial Fibrillation – How to Predict Outcome? –
Maciej Wójcik, Alexander Berkowitsch, Harald Greiss, Sergey Zaltsberg, Dimitri Pajitnev, Nicolas Deubner, Christian W. Hamm, Heinz F. Pitschner, Malte Kuniss, Thomas Neumann

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Ipsilateral Circumferential Radiofrequency Ablation of Atrial Fibrillation With Irrigated Tip Catheter – Long- Term Outcome and Pre-Procedural Predictors –
Maciej Wójcik, Damir Erkapic, Alexander Berkowitsch, Sergey Zaltsberg, Harald Greiss, Jörn Schmitt, Dimitri Pajitnev, Stefan Lehinant, Johannes Rixe, Christian W. Hamm, Heinz F. Pitschner, Malte Kuniss, Thomas Neumann

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Cardiovascular Surgery

Fate of Functional Tricuspid Regurgitation After Mitral Valve Repair for Degenerative Mitral Regurgitation
Takashi Murashita, Yukikatsu Okada, Hideo Kanemitsu, Naoto Fukunaga, Yasunobu Konishi, Ken Nakamura, Yoshito Sakon, Tadaaki Koyama

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Aortic Conduit Valve Model With Controlled Moderate Aortic Regurgitation in Rats – A Technical Modification to Improve Short- and Long-Term Outcome and to Increase the Functional Results –
Hiroshi Munakata, Alexander Assmann, Bhawana Poudel-Bochmann, Kim Horstkötter, Hiroyuki Kamiya, Yutaka Okita, Artur Lichtenberg, Payam Akhyari

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Association Between Renal Function, Diastolic Dysfunction, and Postoperative Atrial Fibrillation Following Cardiac Surgery
Su-Kiat Chua, Kou-Gi Shyu, Ming-Jen Lu, Huei-Fong Hung, Jun-Jack Cheng, Shih-Huang Lee, Chia-Hsun Lin, Hung-Hsing Chao, Huey-Ming Lo

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Epidemiology

Angiopoietin-Like Protein 2 Is Associated With Chronic Kidney Disease in a General Japanese Population – The Hisayama Study –
Tomoko Usui, Toshiharu Ninomiya, Masaharu Nagata, Otowa Takahashi, Yasufumi Doi, Jun Hata, Masayo Fukuhara, Takanari Kitazono, Yuichi Oike, Yutaka Kiyohara

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Prognostic Impact of Nutritional Status in Asymptomatic Patients With Cardiac Diseases – A Report From the CHART-2 Study –
Kotaro Nochioka, Yasuhiko Sakata, Jun Takahashi, Satoshi Miyata, Masanobu Miura, Tsuyoshi Takada, Yoshihiro Fukumoto, Nobuyuki Shiba, Hiroaki Shimokawa for the CHART-2 Investigators

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Imaging

Intimal Flaps Detected by Optical Frequency Domain Imaging in the Proximal Segments of Native Coronary Arteries – An Innocent Bystander? Insights From the TROFI Trial –
Takashi Muramatsu, Hector M. García-García, Yoshinobu Onuma, Yao-Jun Zhang, Christos V. Bourantas, Roberto Diletti, Javaid Iqbal, Maria D. Radu, Yukio Ozaki, Patrick W. Serruys on behalf of the TROFI investigators

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Volumetric Characterization of Human Coronary Calcification by Frequency-Domain Optical Coherence Tomography
Emile Mehanna, Hiram G. Bezerra, David Prabhu, Eric Brandt, Daniel Chamié, Hirosada Yamamoto, Guilherme F. Attizzani, Satoko Tahara, Nienke Van Ditzhuijzen, Yusuke Fujino, Tomoaki Kanaya, Gregory Stefano, Wei Wang, Madhusudhana Gargesha, David Wilson, Marco A. Costa

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Ischemic Heart Disease

Randomized, Double-Blind Trial to Evaluate the Safety of Apixaban With Antiplatelet Therapy After Acute Coronary Syndrome in Japanese Patients (APPRAISE-J)
Hisao Ogawa, Shinya Goto, Masunori Matsuzaki, Shintaro Hiro, Daisuke Shima on behalf of the APPRAISE-J investigators

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Metabolic Disorder

Highly Purified Eicosapentaenoic Acid May Increase Low-Density Lipoprotein Particle Size by Improving Triglyceride Metabolism in Patients With Hypertriglyceridemia
Shigemasa Tani, Ken Nagao, Michiaki Matsumoto, Atsushi Hirayama

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Molecular Cardiology

Somatic MYH7, MYBPC3, TPM1, TNNT2 and TNNI3 Mutations in Sporadic Hypertrophic Cardiomyopathy
Lucía Núñez, Juan Ramón Gimeno-Blanes, María Isabel Rodríguez-García, Lorenzo Monserrat, Esther Zorio, Caroline Coats, Christopher G. McGregor, Juan Pedro Hernandez del Rincón, Alfonso Castro- Beiras, Manuel Hermida-Prieto

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Myocardial Disease

Clinical Characteristics and Natural History of Hypertrophic Cardiomyopathy With Midventricular Obstruction
Georgios K. Efthimiadis, Efstathios D. Pagourelias, Despoina Parcharidou, Thomas Gossios, Vasileios Kamperidis, Efstratios K. Theofilogiannakos, Zoi Pappa, Soultana Meditskou, Stavros Hadjimiltiades, Christodoulos Pliakos, Haralampos Karvounis, Ioannis H. Styliadis

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Pediatric Cardiology and Adult Congenital Heart Disease

Heart Failure With Preserved Ejection Fraction in Children – Hormonal Imbalance Between Aldosterone and Brain Natriuretic Peptide –
Satoshi Masutani, Hirofumi Saiki, Clara Kurishima, Hirotaka Ishido, Masanori Tamura, Hideaki Senzaki

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Pulmonary Circulation

Noninvasive and Simple Assessment of Cardiac Output and Pulmonary Vascular Resistance With Whole-Body Impedance Cardiography Is Useful for Monitoring Patients With Pulmonary Hypertension
Yu Taniguchi, Noriaki Emoto, Kazuya Miyagawa, Kazuhiko Nakayama, Hiroto Kinutani, Hidekazu Tanaka, Toshiro Shinke, Ken-ichi Hirata

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Valvular Heart Disease

Contractile Reserve Determined on Exercise Echocardiography in Patients With Severe Aortic Regurgitation
Sung-Ji Park, Maurice Enriquez-Sarano, Jung-Eun Song, Yung-Joo Lee, Mi-Ran Ha, Sung-A Chang, Jin-Oh Choi, Sang-Chol Lee, Seung Woo Park, Jae K Oh

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Vascular Biology and Vascular Medicine

Tertiary-Butylhydroquinone Upregulates Expression of ATP-Binding Cassette Transporter A1 via Nuclear Factor E2-Related Factor 2/Heme Oxygenase-1 Signaling in THP-1 Macrophage-Derived Foam Cells
Qian Lu, Shi-Lin Tang, Xiao-Yan Liu, Guo-Jun Zhao, Xin-Ping Ouyang, Yun-Cheng Lv, Ping-Ping He, Feng Yao, Wu-Jun Chen, Yan-Yan Tang, Min Zhang, Da-Wei Zhang, Kai Yin, Chao-Ke Tang

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・2399

Images in Cardiovascular Medicine

Coronary Artery Aneurysm After Kawasaki Disease in a Single Coronary Artery
Manatomo Toyono, Daichi Takagi, Jun Oyamada, Shunsuke Shimada, Mieko Aoki-Okazaki, Tsutomu Takahashi

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Respiratory Variation of Vertebral Arterial Flow in a Patient Scheduled for Coronary Artery Bypass Graft Surgery – Lesson From Atypical Subclavian Steal Phenomenon –
Takahiro Anegawa, Hisashi Kai, Kenji Fukuda, Yoshiko Iwamoto, Tomoko Tsuru, Naoki Itaya, Hiroshi Koiwaya, Tomohiro Takeuchi, Yasuyuki Toyama, Toyoharu Oba, Kazuhisa Mawatari, Yasuharu Takeuchi, Motohiro Morioka, Hiroyuki Tanaka, Takafumi Ueno, Tsutomu Imaizumi

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Letters to the Editor

Endothelial Progenitor Cells and Long-Term Prognosis in Patients With Stable Angina Treated With Percutaneous Coronary Intervention
(Letter) Michał Chyrchel, Tomasz Rakowski, Andrzej Surdacki

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(Reply) Francesco Pelliccia

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■月刊誌 Circulation Journal Vol.77 No.9 広告掲載企業様一覧
クリアクター、コアテック、タンボコール、ニトロール、ワソラン（エーザイ株式会社）
サムスカ（大塚製薬株式会社）
プロサイリン、リピディル（科研製薬株式会社）
グルベス（キッセイ薬品工業株式会社）
ウリアデック（株式会社 三和化学研究所）
スイニー（株式会社 三和化学研究所）
ダイアート（株式会社 三和化学研究所）
レザルタス（第一三共株式会社）
ゾシン（大正富山医薬品株式会社）
アイミクス（大日本住友製薬株式会社）
認知症を防ぐために（武田薬品工業株式会社）
テネリア（田辺三菱製薬株式会社）
ミカルディス　他（日本ベーリンガーインゲルハイム（株））
エパデール（持田製薬株式会社）
VaSera、ＦＭ１９０（フクダ電子株式会社）
（順不同）

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