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Message From the Editor-in-Chief

Message From the Editor-in-Chief
Hiroaki Shimokawa

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Cardiovascular Epidemiology in Asia

Epidemiology of Arrhythmias and Sudden Cardiac Death in Asia
Nobuyuki Murakoshi, Kazutaka Aonuma

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Reviews

High-Density Lipoproteins – Multifunctional but Vulnerable Protections from Atherosclerosis –
Wijtske Annema, Arnold von Eckardstein

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Mitochondrial Autophagy – An Essential Quality Control Mechanism for Myocardial Homeostasis –
Robert L. Thomas, Åsa B. Gustafsson

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Roles of Accessory Proteins for Heterotrimeric G-Protein in the Development of Cardiovascular Diseases
Motohiko Sato

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Expanding Role of Delta-Like 4 Mediated Notch Signaling in Cardiovascular and Metabolic Diseases
Daiju Fukuda, Masanori Aikawa

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Editorials

Drug-Eluting Coronary Stents for Left Main Coronary Artery Disease – Is Too Much as Bad as Too Little? –
Tomohiro Sakamoto

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Rho-Kinase in Leukocytes – An Emerging Biomarker for Heart Failure–
Hiroyuki Watanabe, Kenji Iino, Hiroshi Ito

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Omega-3 Polyunsaturated Fatty Acids and Coronary Unstable Plaque – Hint to Further Reduce Coronary Events –
Hiroshi Ito

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Prevalence of Sudden Death and Out-of-Hospital Cardiac Arrest in Infants, Children, and Adolescents – What Does it Imply? –
Masao Yoshinaga

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A New Class of Drug for Pulmonary Arterial Hypertension – Can a Rho-Kinase Inhibitor Break the Stagnation in Treating It? –
Kazuya Miyagawa, Noriaki Emoto

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[¹⁸F]-Fluorodeoxyglucose – A New Imaging Modality for Atherosclerotic Plaque Thrombogenicity –
Koichi Kaikita, Hisao Ogawa

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Original Articles

Arrhythmia/Electrophysiology

Left Ventricular Activation Imaging by 3-Dimensional Speckle-Tracking Echocardiography – Comparison With Electrical Activation Mapping –
Yoshihiro Seo, Hiro Yamasaki, Ryo Kawamura, Tomoko Ishizu, Miyako Igarashi, Yukio Sekiguchi, Hiroshi Tada, Kazutaka Aonuma

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Optimal Strength and Number of Shocks at Upper Limit of Vulnerability Testing Required to Predict High Defibrillation Threshold Without Inducing Ventricular Fibrillation
Kaoru Takami, Akihiro Yoshida, Koji Fukuzawa, Asumi Takei, Kunihiko Kiuchi, Gaku Kanda, Hiroyuki Kumagai, Mitsuru Takami, Satoko Torii-Tanaka, Mitsuaki Itoh, Kimitake Imamura, Ryudo Fujiwara, Atsushi Suzuki, Tomoyuki Nakanishi, Soichiro Yamashita, Akinori Matsumoto, Ken-ichi Hirata

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Cardiovascular Intervention

Seven-Year Clinical Outcomes of Unprotected Left Main Coronary Artery Stenting With Drug-Eluting Stent and Bare-Metal Stent
Shunsuke Kubo, Kazushige Kadota, Takenobu Shimada, Masatomo Ozaki, Tahei Ichinohe, Haruki Eguchi, Koshi Miyake, Yusuke Hyodo, Naoki Saito, Hideaki Otsuji, Suguru Otsuru, Daiji Hasegawa, Yoshikazu Shigemoto, Seiji Habara, Takeshi Tada, Hiroyuki Tanaka, Yasushi Fuku, Harumi Katoh, Hiroyuki Yamamoto, Satoki Fujii, Tsuyoshi Goto, Kazuaki Mitsudo

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Cardiovascular Surgery

Proposal of a Novel Index for Selection of Optimal Annuloplasty Ring Size for Tricuspid Annuloplication
Shuhei Fujita, Hirokuni Arai, Makoto Tomita, Tomohiro Mizuno, Satoru Kawaguchi, Susumu Manabe, Tsuyoshi Hachimaru, Naoto Miyagi

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Right Ventricular and Tricuspid Valve Remodeling After Bidirectional Cavopulmonary Anastomosis
Shinya Ugaki, Nee S. Khoo, David B. Ross, Ivan M. Rebeyka, Ian Adatia

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Heart Failure

Donepezil Markedly Improves Long-Term Survival in Rats With Chronic Heart Failure After Extensive Myocardial Infarction
Meihua Li, Can Zheng, Toru Kawada, Masashi Inagaki, Kazunori Uemura, Toshiaki Shishido, Masaru Sugimachi

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Myocardial Stretch in Early Systole is a Key Determinant of the Synchrony of Left Ventricular Mechanical Activity in Vivo
Giuseppe Caracciolo, Georg Goliasch, Makoto Amaki, Manish Bansal, Ayumi Nakabo, Haruhiko Abe, Luis Scott, Luka Lipar, Gianni Pedrizzetti, Jagat Narula, Partho P. Sengupta

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Implantable Loop Recorder Allows an Etiologic Diagnosis in One-Third of Patients – Results of the Spanish Reveal Registry –
Francisco J. Lacunza-Ruiz, Angel Moya-Mitjans, Jesús Martínez-Alday, Gonzalo Barón-Esquivias, Ricardo Ruiz-Granell, Nuria Rivas-Gándara, Susana González-Enríquez, Juan Leal-del-Ojo, María F. Arcocha- Torres, Julian Pérez-Villacastín, Natalie Garcia-Heil, Arcadi García-Alberola

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Rho-Kinase Activation in Patients With Heart Failure
Zhulanqiqige Do.e, Yoshihiro Fukumoto, Koichiro Sugimura, Yutaka Miura, Shunsuke Tatebe, Saori Yamamoto, Tatsuo Aoki, Kotaro Nochioka, Suvd Nergui, Nobuhiro Yaoita, Kimio Satoh, Masateru Kondo, Makoto Nakano, Yuji Wakayama, Koji Fukuda, Taro Nihei, Yoku Kikuchi, Jun Takahashi, Hiroaki Shimokawa

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Clinical Significance of Abnormal Relaxation Pattern of the Transmitral Flow Velocity Waveform in Older Patients With Preserved Left Ventricular Ejection Fraction
Shohei Kikuchi, Kazuaki Wakami, Toshihiko Goto, Hidekatsu Fukuta, Hiroo Sonoda, Tomomitsu Tani, Nobuyuki Ohte

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Hypertension and Circulatory Control

GABA_B Receptor Gene Transfer Into the Nucleus Tractus Solitarii Induces Chronic Blood Pressure Elevation in Normotensive Rats
Bo Li, Qing Liu, Chengluan Xuan, Lirong Guo, Ruofan Shi, Qi Zhang, Stephen T. O’Rourke, Kexiang Liu, Chengwen Sun

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Low Salt Intake and Changes in Serum Sodium Levels in the Combination Therapy of Low-Dose Hydrochlorothiazide and Angiotensin II Receptor Blocker
Masafumi Nakayama, Hirofumi Tomiyama, Iwao Kuwajima, Tetsushi Saito, Yohei Hokama, Yuji Fujii, Tadanori Shimizu, Tohru Nakayama, Akira Yamashina, Yoshifusa Aizawa

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Ischemic Heart Disease

Regression of Luminal Stenosis at the Site of Silent Plaque Disruption in the Era of Optimal Medical Therapy – Low High-Density Lipoprotein Cholesterol Level Is a Potential Risk of Stenosis Progression –
Takayoshi Nemoto, Yasunori Ueda, Koshi Matsuo, Mayu Nishio, Akio Hirata, Mitsutoshi Asai, Ayaka Murakami, Kazunori Kashiwase, Kazuhisa Kodama

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Association Between Serum Levels of n-3 Polyunsaturated Fatty Acids and Coronary Plaque Detected by Coronary Computed Tomography Angiography in Patients Receiving Statin Therapy
Yoji Urabe, Hideya Yamamoto, Toshiro Kitagawa, Hiroto Utsunomiya, Hiroshi Tsushima, Fuminari Tatsugami, Kazuo Awai, Yasuki Kihara

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Myocardial Disease

Thromboxane A₂ Mediates Iron-Overload Cardiomyopathy in Mice Through Calcineurin-Nuclear Factor of Activated T Cells Signaling Pathway
Heng Lin, Hsiao-Fen Li, Wei-Shiung Lian, Hsi-Hsien Chen, Yi-Fan Lan, Pei-Fang Lai, Ching-Feng Cheng

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Pediatric Cardiology and Adult Congenital Heart Disease

Regional Variation in Survival Following Pediatric Out-of-Hospital Cardiac Arrest
Yoshio Okamoto, Taku Iwami, Tetsuhisa Kitamura, Masahiko Nitta, Atsushi Hiraide, Tsuneo Morishima, Takashi Kawamura

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Vitamin C Prevents Intrauterine Programming of in Vivo Cardiovascular Dysfunction in the Rat
Andrew D. Kane, Emilio A. Herrera, Emily J. Camm, Dino A. Giussani

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Pulmonary Circulation

Diuretics in Normotensive Patients With Acute Pulmonary Embolism and Right Ventricular Dilatation
Julien Ternacle, Romain Gallet, Armand Mekontso-Dessap, Guy Meyer, Bernard Maitre, Alexandre Bensaid, Priscille Jurzak, Pascal Gueret, Jean-Luc Dubois Randé, Pascal Lim

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Double-Blind, Placebo-Controlled Clinical Trial With a Rho-Kinase Inhibitor in Pulmonary Arterial Hypertension – A Pilot Efficacy Trial –
Yoshihiro Fukumoto, Norikazu Yamada, Hiromi Matsubara, Minori Mizoguchi, Kazuaki Uchino, Atsushi Yao, Yasuki Kihara, Mitsuhiro Kawano, Hiroshi Watanabe, Yutaka Takeda, Takeshi Adachi, Shinobu Osanai, Nobuhiro Tanabe, Teruo Inoue, Akihiro Kubo, Yuri Ota, Koichiro Fukuda, Takeshi Nakano, Hiroaki Shimokawa

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Vascular Biology and Vascular Medicine

Arterial ¹⁸F-Fluorodeoxyglucose Uptake Reflects Balloon Catheter-Induced Thrombus Formation and Tissue Factor Expression via Nuclear Factor-κB in Rabbit Atherosclerotic Lesions
Atsushi Yamashita, Yan Zhao, Songji Zhao, Yunosuke Matsuura, Chihiro Sugita, Takashi Iwakiri, Nozomi Okuyama, Kazuyo Ohe, Chihiro Koshimoto, Keiichi Kawai, Nagara Tamaki, Yuji Kuge, Yujiro Asada

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Letters to the Editor

The J-ROCKET AF Study: A Matter of Ethnicity or a Matter of Weight?
(Letter) Marcial Delgado-Fernández

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(Reply) Masatsugu Hori, Mariko Kajikawa

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■月刊誌 Circulation Journal Vol.77 No.10 広告掲載企業様一覧
クリアクター、コアテック、タンボコール、ニトロール、ワソラン（エーザイ株式会社）
サムスカ（大塚製薬株式会社）
プロサイリン（科研製薬株式会社）
ウリアデック（株式会社三和化学研究所）
セイブル（株式会社三和化学研究所）
オルメテック（第一三共株式会社）
ルプラック（大正富山医薬品株式会社）
アジルバ（武田薬品工業株式会社）
テネリア（田辺三菱製薬株式会社）
メインテート（田辺三菱製薬株式会社）
ビソノテープ（トーアエイヨー株式会社）
ラジレス（ノバルティスファーマ株式会社）
アテレック（持田製薬株式会社）
ＶaSera　FM-190（フクダ電子株式会社）
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