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Message From the Editor-in-Chief

Rapid Publication and Announcement of the 2014 JCS Meeting Activities
Hiroaki Shimokawa

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・781

Reviews

Modeling Inherited Cardiac Disorders – A Cell Is Worth a Thousand Genes –
Karim Sallam, Kazuki Kodo, Joseph C. Wu

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・784

Sphingosine-1-Phosphate as a Potential Target for the Treatment of Myocardial Infarction
Christian Waeber, Thomas Walther

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・795

Regulation of Mitochondrial Dynamics and Cell Fate
Rimpy Dhingra, Lorrie A. Kirshenbaum

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・803

Aortic Regurgitation After Transcatheter Aortic Valve Replacement – Nothing to Worry About Anymore? –
Nikos Werner, Jan-Malte Sinning

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・811

Incretin Therapy and Heart Failure
Jun-ichi Oyama, Koichi Node

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・819

Editorials

Mechanical Valves and Anticoagulation in Pregnancy
Kentaro Honda, Yoshitaka Okamura

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・825

New Biomarker in Heart Failure With Reduced Ejection Fraction
Yoshihiro Fukumoto

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・827

Immediate and Short-Term Use of Tolvaptan for Acute Decompensated Heart Failure
Kaoru Dohi, Masaaki Ito

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・829

Late Gadolinium Enhancement and Prognosis of Hypertrophic Cardiomyopathy
Hajime Sakuma

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・832

Role of Electrocardiography in the Diagnosis and Management of Takotsubo Cardiomyopathy
Satoshi Kurisu, Yasuki Kihara

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・835

Significant Association Between Periodontitis and Cardiovascular Risk
Kazuo Kimura, Bonpei Takase

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・837

Alcohol and Atrial Fibrillation – Transient Trigger or Lifetime Risk? –
Shinya Suzuki

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・839

What Is the Appropriate Strategy for Coronary Revascularization in Hemodialysis Patient in Japan?
Shigemasa Tani, Ken Nagao, Atsushi Hirayama

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・841

Late Breaking Cohort Studies (JCS 2014)

Efficacy and Safety of Tolvaptan in Heart Failure Patients With Volume Overload – An Interim Result of Post-Marketing Surveillance in Japan –
Koichiro Kinugawa, Naoki Sato, Takayuki Inomata, Toshiyuki Shimakawa, Noriaki Iwatake, Kazuki Mizuguchi

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・844

Original Articles

Arrhythmia/Electrophysiology

Impact of Renal Dysfunction on Clinical Outcome in Patients With Low Risk of Atrial Fibrillation
Wen-Yu Lin, Yenn-Jiang Lin, Fa-Po Chung, Tze-Fan Chao, Jo-Nan Liao, Shih-Lin Chang, Li-Wei Lo, Yu- Feng Hu, Chern-En Chiang, Shu-Meng Cheng, Wei-Shiang Lin, Shih-Ann Chen

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・853

Counterclockwise Heart Rotation Affects Variation in Successful Ablation Line Position in Common Atrial Flutter
Takeshi Machino, Hiroshi Tada, Yukio Sekiguchi, Yoshihisa Naruse, Kenji Kuroki, Hiro Yamasaki, Miyako Igarashi, Kentaro Yoshida, Akihiko Nogami, Kazutaka Aonuma

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・859

Comparison of the Axillary Venous Approach and Subclavian Venous Approach for Efficacy of Permanent Pacemaker Implantation – 8-Year Follow-up Results –
Ki-Hun Kim, Kyoung-Min Park, Gi-Byoung Nam, Dae-Kyeong Kim, Minkyung Oh, HyungOh Choi, Taek Jong Hong, Bo-Min Park, Guang-Won Seo, Pil-Sang Song, Dong-Kie Kim, Sang-Hoon Seol, Doo-IL Kim, You-Ho Kim, Kee-Joon Choi

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・865

Impact of Atrial Remodeling on the Outcome of Radiofrequency Catheter Ablation of Paroxysmal Atrial Fibrillation
Koichiro Ejima, Ken Kato, Kotaro Arai, Keiko Fukushima, Noritoshi Fukushima, Tsuyoshi Suzuki, Kentaro Yoshida, Toshiaki Nuki, Shoko Uematsu, Hiromi Hoshi, Tetsuyuki Manaka, Kyomi Ashihara, Morio Shoda, Nobuhisa Hagiwara

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・872

Cardiovascular Surgery

Analysis of Anticoagulant Therapy by Unfractionated Heparin During Pregnancy After Mechanical Valve Replacement
Hiroaki Tanaka, Kayo Tanaka, Chizuko Kamiya, Naoko Iwanaga, Shinji Katsuragi, Jun Yoshimatsu

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・878

Long-Term Outcome of the Carpentier-Edwards Pericardial Valve in the Aortic Position in Japanese Patients
Kenji Minakata, Shiro Tanaka, Yohei Okawa, Mitsuomi Shimamoto, Tatsuo Kaneko, Yoshiharu Takahara, Hitoshi Yaku, Kazuo Yamanaka, Akihiko Usui, Nobushige Tamura, Ryuzo Sakata

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・882

Heart Failure

High-Sensitivity Cardiac Troponin T Predicts Non-Cardiac Mortality in Heart Failure
Yuichi Nakamura, Akiomi Yoshihisa, Mai Takiguchi, Takeshi Shimizu, Hiroyuki Yamauchi, Shoji Iwaya, Takashi Owada, Makiko Miyata, Satoshi Abe, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Koichi Sugimoto, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-ichi Saitoh, Yasuchika Takeishi

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・890

Higher Level at Admission and Subsequent Decline in Hemoglobin in Patients With Acute Pulmonary Edema
Masaaki Konishi, Yasushi Matsuzawa, Hiroyuki Suzuki, Eiichi Akiyama, Noriaki Iwahashi, Nobuhiko Maejima, Mitsuaki Endo, Kengo Tsukahara, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kentaro Sakamaki, Satoshi Morita, Satoshi Umemura, Kazuo Kimura

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・896

Circulating Thrombospondin-2 Reflects Disease Severity and Predicts Outcome of Heart Failure With Reduced Ejection Fraction
Shinsuke Hanatani, Yasuhiro Izumiya, Seiji Takashio, Yuichi Kimura, Satoshi Araki, Taku Rokutanda, Kenichi Tsujita, Eiichiro Yamamoto, Tomoko Tanaka, Megumi Yamamuro, Sunao Kojima, Shinji Tayama, Koichi Kaikita, Seiji Hokimoto, Hisao Ogawa

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・903

Immediate Administration of Tolvaptan Prevents the Exacerbation of Acute Kidney Injury and Improves the Mid-Term Prognosis of Patients With Severely Decompensated Acute Heart Failure
Akihiro Shirakabe, Noritake Hata, Masanori Yamamoto, Nobuaki Kobayashi, Takuro Shinada, Kazunori Tomita, Masafumi Tsurumi, Masato Matsushita, Hirotake Okazaki, Yoshiya Yamamoto, Shinya Yokoyama, Kuniya Asai, Wataru Shimizu

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・911

Hypertension and Circulatory Control

Relationship Between Intrinsic Cardiac Autonomic Ganglionated Plexi and the Atrial Fibrillation Nest
Hung-Yu Chang, Li-Wei Lo, Yenn-Jiang Lin, Shih-Huang Lee, Chuen-Wang Chiou, Shih-Ann Chen

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・922

Imaging

Prognostic Value of Late Gadolinium Enhancement on Cardiac Magnetic Resonance Imaging in Japanese Hypertrophic Cardiomyopathy Patients
Yasuki Hen, Nobuo Iguchi, Yuko Utanohara, Kaori Takada, Haruhiko Machida, Morimasa Takayama, Tetsuya Sumiyoshi

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・929

Molecular Cardiology

A Novel HCN4 Mutation, G1097 W, Is Associated With Atrioventricular Block
Jun Zhou, Wei-Guang Ding, Takeru Makiyama, Akashi Miyamoto, Yuichi Matsumoto, Hiromi Kimura, Yasuhiro Tarutani, Jin Zhao, Jie Wu, Wei-Jin Zang, Hiroshi Matsuura, Minoru Horie

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・938

Myocardial Disease

J Wave and Fragmented QRS Formation During the Hyperacute Phase in Takotsubo Cardiomyopathy – Possible Markers for Severity of Myocardial Damage –
Masato Shimizu, Mitsuhiro Nishizaki, Noriyoshi Yamawake, Hiroyuki Fujii, Harumizu Sakurada, Mitsuaki Isobe, Masayasu Hiraoka

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・943

Preventive Medicine

Poor Oral Health, That Is, Decreased Frequency of Tooth Brushing, Is Associated With Endothelial Dysfunction
Masato Kajikawa, Ayumu Nakashima, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi Iwamoto, Takeshi Matsumoto, Takayuki Hidaka, Yasuki Kihara, Kazuaki Chayama, Chikara Goto, Akira Taguchi, Kensuke Noma, Yukihito Higashi

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・950

Heavy Alcohol Consumption and Risk of Atrial Fibrillation – The Circulatory Risk in Communities Study (CIRCS) –
Fumihiko Sano, Tetsuya Ohira, Akihiko Kitamura, Hironori Imano, Renzhe Cui, Masahiko Kiyama, Takeo Okada, Kazumasa Yamagishi, Tomoko Sankai, Takeshi Tanigawa, Kazuomi Kario, Hiroyasu Iso

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・955

Pulmonary Circulation

Estimation of Right Atrial Pressure on Inferior Vena Cava Ultrasound in Asian Patients
Seitetsu L. Lee, Masao Daimon, Takayuki Kawata, Takahide Kohro, Koichi Kimura, Tomoko Nakao, Daisuke Koide, Masafumi Watanabe, Tsutomu Yamazaki, Issei Komuro

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・962

Combination Therapy With Fasudil and Sildenafil Ameliorates Monocrotaline-Induced Pulmonary Hypertension and Survival in Rats
Md. Elias-Al-Mamun, Kimio Satoh, Shin-ichi Tanaka, Toru Shimizu, Suvd Nergui, Satoshi Miyata, Yoshihiro Fukumoto, Hiroaki Shimokawa

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・967

Regenerative Medicine

Endothelial Progenitor Cells in Morbid Obesity – Pathogenetic Implications –
Francesca Graziani, Antonio Maria Leone, Eloisa Basile, Pio Cialdella, Alessandra Tritarelli, Roberta Della Bona, Giovanna Liuzzo, Giuseppe Nanni, Amerigo Iaconelli, Antonio Iaconelli, Geltrude Mingrone, Luigi Marzio Biasucci, Filippo Crea

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・977

Renal Disease

Long-Term Clinical Outcome After Surgical or Percutaneous Coronary Revascularization in Hemodialysis Patients
Yoshitaka Kumada, Hideki Ishii, Toru Aoyama, Daisuke Kamoi, Yoshihiro Kawamura, Takashi Sakakibara, Haruhiko Nogaki, Hiroshi Takahashi, Toyoaki Murohara

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・986

Valvular Heart Disease

Quantitative Proteomics of Changes in Energy Metabolism-Related Proteins in Atrial Tissue From Valvular Disease Patients With Permanent Atrial Fibrillation
Tao Tu, Shenghua Zhou, Zhenjiang Liu, Xuping Li, Qiming Liu

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・993

Images in Cardiovascular Medicine

Efficacy of Percutaneous Balloon Aortic Valvuloplasty Visualized on Computed Tomography
Atsushi Mizuno, Kohei Kawazoe, Koichiro Niwa

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1002

Prosthetic Valve Thrombosis Caused by Heparin-Induced Thrombocytopenia Thrombosis During Pregnancy
Tomitaka Higa, Hiroyuki Okura, Kazuo Tanemoto, Kiyoshi Yoshida

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1004

Inflammatory Myofibroblastic Tumor of the Heart – Overlap With IgG4-Related Disease? –
Hidemichi Kouzu, Takayuki Miki, Masashi Mizuno, Yukishige Kimura, Atsuko Muranaka, Satoshi Yuda, Yoshiko Keira, Tadashi Hasegawa, Yasuko Miyaki, Nobuyuki Takagi, Tetsuya Higami, Tetsuji Miura

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1006

Letters to the Editor

Is High Leukocyte Count Synonymous With the Presence of Endothelial Dysfunction or Atherosclerosis?
(Letter) Yavuzer Koza

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1009

(Reply) Jing Li, Amir Lerman

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1010

Association of Angulation at Stent Edge and Plaque Increase or Negative Remodeling
(Letter) Hiroshi Yamaguchi, Yoshihiko Atsuchi, Hideaki Kaneda

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1011

(Reply) Yun Gi Kim, Hyo-Soo Kim, Il-Young Oh

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1012

Corrigendum

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1013

■月刊誌 Circulation Journal Vol.78 No.4 広告掲載企業様一覧
クリアクター、コアテック、タンボコール、ニトロール、ワソラン（エーザイ株式会社）
サムスカ（大塚製薬株式会社）
プロサイリン（科研製薬株式会社）
ダイアート（株式会社三和化学研究所）
オルメテック（第一三共株式会社）
企業広告（第一三共株式会社）
ルプラック（大正富山医薬品株式会社）
アジルバ（武田薬品工業株式会社）
メインテート（田辺三菱製薬株式会社）
フェブリク（帝人ファーマ株式会社）
ビソノテープ（トーアエイヨー株式会社）
アテレック（持田製薬株式会社）
イグザレルト錠（バイエル薬品株式会社）
ＶaSera、FM-190（フクダ電子株式会社）
（順不同）

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