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Message From the Editor-in-Chief

Rapid Publication and Announcement of the 2015 JCS Meeting Activities
Hiroaki Shimokawa

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Focus Reviews on Functional Testings

Coronary Functional Tests in the Catheterization Laboratory – Pathophysiological and Clinical Relevance –
Giampaolo Niccoli, Giancarla Scalone, Filippo Crea

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・676

Secondary Prevention Strategy of Cardiovascular Disease Using Endothelial Function Testing
Yasushi Matsuzawa, Raviteja R. Guddeti, Taek-Geun Kwon, Lilach O. Lerman, Amir Lerman

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・685

Focus Reviews on Cardiovascular Intervention

Transcatheter Aortic Valve-in-Valve Implantation for Patients With Degenerative Surgical Bioprosthetic Valves
Danny Dvir, John G. Webb

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・695

Primary Stenting in Femoropopliteal Occlusive Disease – What Is the Appropriate Role? –
Wai-ki Yiu, Michael S. Conte

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・704

Focus Reviews on Imaging

Role of Cardiac Multidetector Computed Tomography Beyond Coronary Angiography
Akira Sato, Kazutaka Aonuma

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・712

Echocardiographic Assessment of the Cardiac Amyloidoses
Jun Koyama, Shu-ichi Ikeda, Uichi Ikeda

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・721

Speckle Tracking Echocardiography – Quo Vadis? –
Masaaki Uematsu

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・735

Early Detection of Vulnerable Atherosclerotic Plaque for Risk Reduction of Acute Aortic Rupture and Thromboemboli and Atheroemboli Using Non-Obstructive Angioscopy
Sei Komatsu, Tomoki Ohara, Satoru Takahashi, Mitsuhiko Takewa, Hitoshi Minamiguchi, Atsuko Imai, Yasuhiko Kobayashi, Nobuzo Iwa, Chikao Yutani, Atsushi Hirayama, Kazuhisa Kodama

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・742

Editorials

How Can We Predict Reduced Fractional Flow Reserve Using Coronary Lesion Characteristics?
Tomonori Itoh

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・751

Lipid Core Abutting Lumen – Optical Coherence Tomography-Verified Thin-Cap Fibroatheroma Surrogate –
Ari Pollack, Annapoorna S. Kini, Jagat Narula

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・754

Evaluation of the Genetic Risk of Hypertension-Related Diseases
Hironori Nakagami

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・756

Takotsubo Cardiomyopathy and Left Ventricular Outflow Tract Obstruction
Masaharu Ishihara

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Fetal Bradycardia Associated With Congenital Heart Defects – Is There a Clinicohistological Correlation? –
Kazuhiro Takahashi

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・761

Timing of Anticoagulation Therapy in Patients With Acute Cardioembolic Stroke
Hiroshi Yamagami, Kazunori Toyoda

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・763

Does Major Noncardiac Surgery Accelerate the Progression of Aortic Stenosis? – Role of Inflammation –
Makoto Amaki, Toshihisa Anzai

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・766

Pioglitazone Revisited to Illuminate Contemporary Vascular Reparative Therapy in the Era of Drug- Eluting Stents
Toshiro Shinke

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・768

Original Articles

Cardiovascular Surgery

Attenuation in Peripheral Endothelial Function After Continuous Flow Left Ventricular Assist Device Therapy Is Associated With Cardiovascular Adverse Events
Tal Hasin, Yasushi Matsuzawa, Raviteja R. Guddeti, Tatsuo Aoki, Taek-Geun Kwon, Sarah Schettle, Ryan J. Lennon, Ramesh G. Chokka, Amir Lerman, Sudhir S. Kushwaha

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・770

Aortic Wrapping for a Dilated Ascending Aorta in Bicuspid Aortic Stenosis
Min Suk Choi, Dong Seop Jeong, Hae Young Lee, Kiick Sung, Wook Sung Kim, Young Tak Lee, Pyo Won Park

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・778

Heart Failure

Impact of Peripheral Artery Disease on Prognosis in Hospitalized Heart Failure Patients
Yuichi Nakamura, Hiroyuki Kunii, Akiomi Yoshihisa, Mai Takiguchi, Takeshi Shimizu, Hiroyuki Yamauchi, Shoji Iwaya, Takashi Owada, Satoshi Abe, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Koichi Sugimoto, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-ichi Saitoh, Yasuchika Takeishi

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・785

Hypertension and Circulatory Control

Comparable Accuracy of Micro-Electromechanical Blood Flowmetry-Based Analysis vs. Electrocardiography- Based Analysis in Evaluating Heart Rate Variability
Terukazu Akiyama, Tatsuya Miyazaki, Hiroki Ito, Hirofumi Nogami, Eiji Higurashi, Shin-ichi Ando, Renshi Sawada

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・794

Imaging

Coronary Angiographic Characteristics That Influence Fractional Flow Reserve
Makoto Natsumeda, Gaku Nakazawa, Tsutomu Murakami, Sho Torii, Takeshi Ijichi, Yohei Ohno, Naoki Masuda, Norihiko Shinozaki, Nobuhiko Ogata, Fuminobu Yoshimachi, Yuji Ikari

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・802

Thin Cap Fibroatheroma Defined as Lipid Core Abutting Lumen (LCAL) on Integrated Backscatter Intravascular Ultrasound – Comparison With Optical Coherence Tomography and Correlation With Peri-Procedural Myocardial Infarction –
Yukio Ozaki, Masaya Ohota, Tevfik F. Ismail, Masanori Okumura, Masato Ishikawa, Takashi Muramatsu

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・808

Ischemic Heart Disease

Echocardiographic Epicardial Fat Thickness Is Associated With Coronary Artery Calcification – Results From the CAESAR Study –
Byung Jin Kim, Bum Soo Kim, Jin Ho Kang

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Coronary Microvascular Dysfunction in Asymptomatic Patients Affected by Systemic Sclerosis – Limited vs. Diffuse Form –
Alessia Faccini, Eustachio Agricola, Michele Oppizzi, Alberto Margonato, Maurizio Galderisi, Maria Grazia Sabbadini, Stefano Franchini, Paolo G Camici

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Molecular Cardiology

Heterogeneous Effects of Association Between Blood Pressure Loci and Coronary Artery Disease in East Asian Individuals
Fumihiko Takeuchi, Masato Isono, Ken Yamamoto, Mitsuhiro Yokota, Koichi Akiyama, Tomohiro Katsuya, Hyo-Soo Kim, Jeong Euy Park, Yangsoo Jang, Ji-Young Lee, AGEN Consortium, Jong-Young Lee, Norihiro Kato

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・830

Myocardial Disease

Clinical Impact of Left Ventricular Outflow Tract Obstruction in Takotsubo Cardiomyopathy
Tetsuma Kawaji, Hiroki Shiomi, Takeshi Morimoto, Junichi Tazaki, Masao Imai, Naritatsu Saito, Takeru Makiyama, Satoshi Shizuta, Koh Ono, Takeshi Kimura

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・839

Notched QRS for the Assessment of Myocardial Fibrosis in Hypertrophic Cardiomyopathy
Tatsuya Kawasaki, Kuniyasu Harimoto, Sakiko Honda, Yoshimi Sato, Michiyo Yamano, Shigeyuki Miki, Tadaaki Kamitani

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・847

Pediatric Cardiology and Adult Congenital Heart Disease

Fetal Bradyarrhythmia Associated With Congenital Heart Defects – Nationwide Survey in Japan –
Takekazu Miyoshi, Yasuki Maeno, Haruhiko Sago, Noboru Inamura, Satoshi Yasukouchi, Motoyoshi Kawataki, Hitoshi Horigome, Hitoshi Yoda, Mio Taketazu, Makio Shozu, Masaki Nii, Hitoshi Kato, Akiko Hagiwara, Akiko Omoto, Wataru Shimizu, Isao Shiraishi, Heima Sakaguchi, Kunihiro Nishimura, Michikazu Nakai, Keiko Ueda, Shinji Katsuragi, Tomoaki Ikeda

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・854

Stroke

Early Administration of Non-Vitamin K Antagonist Oral Anticoagulants for Acute Ischemic Stroke Patients With Atrial Fibrillation in Comparison With Warfarin Mostly Combined With Heparin
Eiichi Nomura, Tomohiko Ohshita, Eiji Imamura, Shinichi Wakabayashi, Hiroshi Kajikawa, Naohisa Hosomi, Masayasu Matsumoto

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・862

Valvular Heart Disease

Major Non-Cardiac Surgery Is a Risk Factor for Rapid Hemodynamic Progression of Non-Rheumatic Aortic Stenosis
Reiko Mizuno, Shin-taro Yamagami, Tsukimi Higashi, Yasuki Nakada, Yukiji Takeda, Satoshi Okayama, Shinichi Fujimoto, Yoshihiko Saito

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Tricuspid Annular Dynamics Before and After Tricuspid Annuloplasty – Three-Dimensional Transesophageal Echocardiography –
Hiroyuki Nishi, Koichi Toda, Shigeru Miyagawa, Yasushi Yoshikawa, Satsuki Fukushima, Masashi Kawamura, Daisuke Yoshioka, Tetsuya Saito, Takayoshi Ueno, Toru Kuratani, Yoshiki Sawa

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・873

Vascular Biology and Vascular Medicine

Pioglitazone Increases Circulating MicroRNA-24 With Decrease in Coronary Neointimal Hyperplasia in Type 2 Diabetic Patients – Optical Coherence Tomography Analysis –
Soon Jun Hong, Seung Cheol Choi, Jae Young Cho, Hyung Joon Joo, Jae Hyoung Park, Cheol Woong Yu, Do-Sun Lim

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・880

Rapid Communication

Pulmonary Embolism Severity Index and Simplified Pulmonary Embolism Severity Index Risk Scores Are Useful to Predict Mortality in Japanese Patients With Pulmonary Embolism
Atsushi Mizuno, Takeshi Yamamoto, Yasuhiro Tanabe, Toru Obayashi, Morimasa Takayama, Ken Nagao, Tokyo CCU Network Scientific Committee

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・889

Images in Cardiovascular Medicine

Surgical Repair of Aorta-Right Atrial Tunnel in an Adult
Yuzo Katayama, Tsukasa Ozawa, Atsushi Iga, Shinji Hisatake, Yoshinori Watanabe

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・892

Percutaneous Antegrade Mitral Paravalvular Leak Closure Through Porcelain Atrial Septum – First Percutaneous Paravalvular Leak Closure in Japan –
Hidehiko Hara, Yasushi Matsumoto, Takashi Matsumoto, Saibal Kar, Go Hashimoto, Tadashi Araki, Yoshinori Nagashima, Kenji Yamazaki, Masahide Tokue, Yoshinari Enomoto, Fumiyuki Hayashi, Yoshiyuki Yazaki, Raisuke Iijima, Makoto Suzuki, Kaoru Sugi, Masato Nakamura

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・894

Letters to the Editor

Is High-Dose Catecholamine Administration in Small Animals an Appropriate Model for Takotsubo Syndrome?
(Letter) Paolo Angelini, Jonathan M. Tobis

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(Reply) Peter T. Wright, Matthew H. Tranter, Andrew Morley-Smith, Alexander R. Lyon

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■月刊誌 Circulation Journal Vol.79 No.4 広告掲載企業様一覧
フォシーガ（アストラゼネカ株式会社）
クリアクター、コアテック、タンボコール、ニトロール、ワソラン（エーザイ株式会社）
パリエット（エーザイ株式会社）
プロサイリン（科研製薬株式会社）
ウリアデック（株式会社 三和化学研究所）
ダイアート（株式会社 三和化学研究所）
オルメテック（第一三共株式会社）
アジルバ、ザクラス（武田薬品工業株式会社）
メインテート（田辺三菱製薬株式会社）
フェブリク（帝人ファーマ株式会社）
クロピドグレル（テバ製薬株式会社）
ビソノテープ（トーアエイヨー株式会社）
VaSera、ＦＭ１９０（フクダ電子株式会社）
アテディオ（持田製薬株式会社）
ドクターソフト（株式会社油井コンサルティング）
統合型統計パッケージ（株式会社ライトストーン）
（順不同）

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