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Message From the Editor-in-Chief

Message From the Editor-in-Chief
Hiroaki Shimokawa

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1397

JCS Statement

Aiming for Zero Deaths: Prevention of Sudden Cardiac Death in Schools – Statement From the AED Committee of the Japanese Circulation Society –
Hideo Mitamura, Taku Iwami, Yoshihide Mitani, Satoshi Takeda, Seiji Takatsuki

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1398

Focus Reviews on Molecular Cardiology

Maturation-Based Model of Arrhythmogenic Right Ventricular Dysplasia Using Patient-Specific Induced Pluripotent Stem Cells
Jian-Yan Wen, Chuan-Yu Wei, Khooshbu Shah, Johnson Wong, Cheng Wang, Huei-Sheng Vincent Chen

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1402

Genetic Variation in Cardiomyopathy and Cardiovascular Disorders
Elizabeth M. McNally, Megan J. Puckelwartz

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1409

Reviews

Pregnancy and Delivery in Women With Congenital Heart Disease
Carole A. Warnes

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1416

The Quest for the Adult Cardiac Stem Cell
Michela Noseda, Marta Abreu-Paiva, Michael D. Schneider

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1422

Structural and Functional Coronary Artery Abnormalities in Patients With Vasospastic Angina Pectoris
Peter Ong, Ahmed Aziz, Henrik Steen Hansen, Eva Prescott, Anastasios Athanasiadis, Udo Sechtem

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1431

Editorials

Fountain of Youth in the Aorta
Hiroki Aoki

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1439

Use of Oral Anticoagulants According to the Degree of Renal Impairment in Japanese Patients With Atrial Fibrillation – Which Non-Vitamin K Antagonist Oral Anticoagulant to Select? –
Takanori Ikeda

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1441

Could Circulatory Syndecan-1 Be a Predictable Biomarker for Acute Kidney Injury in Patients With Acute Decompensated Heart Failure?
Daisuke Sueta, Seiji Hokimoto

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1444

Blood Urea Nitrogen/Creatinine Ratio in Acute Heart Failure Patients
Nobuyuki Shiba

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Different Implications of Functional Tricuspid Regurgitation Between Heart Failure (HF) With Reduced Ejection Fraction (EF) and HF With Preserved EF
Osamu Tsukamoto, Masafumi Kitakaze

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1448

How Should We Evaluate the Activity of Myocardial Inflammation and Guide Corticosteroid Treatment in Patients With Cardiac Sarcoidosis?
Yoshikazu Yazaki

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1450

Impact of Demographic Changes on the Natural Course, Features and Prognosis of Critical Limb Ischemia
Nobuyoshi Azuma

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1453

Why Is Proteinuria an Independent Risk Factor for Contrast-Induced Nephropathy?
Fumiki Yoshihara

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1456

Estimating the Prognosis of Patients With Aortic Stenosis in the Current Japanese Population
Kyung-Duk Min

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1458

Original Articles

Aortic Disease

Human Vascular Wall Mesenchymal Stromal Cells Contribute to Abdominal Aortic Aneurysm Pathogenesis Through an Impaired Immunomodulatory Activity and Increased Levels of Matrix Metalloproteinase-9
Carmen Ciavarella, Francesco Alviano, Enrico Gallitto, Francesca Ricci, Marina Buzzi, Claudio Velati, Andrea Stella, Antonio Freyrie, Gianandrea Pasquinelli

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1460

Omega 3 Polyunsaturated Fatty Acids Suppress the Development of Aortic Aneurysms Through the Inhibition of Macrophage-Mediated Inflammation
Takuma Yoshihara, Kazunori Shimada, Kosuke Fukao, Eiryu Sai, Yayoi Sato-Okabayashi, Rie Matsumori, Tomoyuki Shiozawa, Hamad Alshahi, Tetsuro Miyazaki, Norihiro Tada, Hiroyuki Daida

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1470

Arrhythmia/Electrophysiology

High Atrial Defibrillation Threshold With Internal Cardioversion Indicates Arrhythmogenicity of Superior Vena Cava in Non-Long-Standing Persistent Atrial Fibrillation
Kensuke Ihara, Takeshi Sasaki, Yasuhiro Shirai, Susumu Tao, Shingo Maeda, Mihoko Kawabata, Tetsuo Sasano, Yasuhiro Yokoyama, Mitsuaki Isobe, Kenzo Hirao

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1479

Short-Term Safety and Plasma Concentrations of Edoxaban in Japanese Patients With Non-Valvular Atrial Fibrillation and Severe Renal Impairment
Yukihiro Koretsune, Takeshi Yamashita, Tetsuya Kimura, Masayuki Fukuzawa, Kenji Abe, Masahiro Yasaka

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1486

Cardiovascular Intervention

Usefulness of a Simple Clinical Risk Prediction Method, Modified ACEF Score, for Transcatheter Aortic Valve Implantation
Takahide Arai, Thierry Lefèvre, Kentaro Hayashida, Yusuke Watanabe, Stephen A. O’Connor, Thomas Hovasse, Mauro Romano, Philippe Garot, Erik Bouvier, Bernard Chevalier, Marie-Claude Morice

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1496

Cardiovascular Surgery

Aortic Valve Reconstruction Using Autologous Pericardium for Aortic Stenosis
Shigeyuki Ozaki, Isamu Kawase, Hiromasa Yamashita, Shin Uchida, Mikio Takatoh, So Hagiwara, Nagaki Kiyohara

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1504

Heart Failure

Syndecan-1 in Acute Decompensated Heart Failure – Association With Renal Function and Mortality –
Fernanda Macedo de Oliveira Neves, Gdayllon Cavalcante Meneses, Nazareth Ermínia Araujo Sousa, Ramon Róseo Paula Pessoa Bezerra de Menezes, Marcelo Coelho Parahyba, Alice Maria Costa Martins, Alexandre Braga Libório

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1511

Risk Stratification of Acute Kidney Injury Using the Blood Urea Nitrogen/Creatinine Ratio in Patients With Acute Decompensated Heart Failure
Yoichi Takaya, Fumiki Yoshihara, Hiroyuki Yokoyama, Hideaki Kanzaki, Masafumi Kitakaze, Yoichi Goto, Toshihisa Anzai, Satoshi Yasuda, Hisao Ogawa, Yuhei Kawano

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1520

Tricuspid Regurgitation and Mortality Risk Across Left Ventricular Systolic Function in Acute Heart Failure
Enrique Santas, Francisco Javier Chorro, Gema Miñana, José Méndez, Jaime Muñoz, David Escribano, Sergio García-Blas, Ernesto Valero, Vicent Bodí, Eduardo Núñez, Juan Sanchis, Julio Núñez

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1526

Imaging

Development of an Image-Based Modeling System to Investigate Evolutional Geometric Changes of a Stent Graft in an Abdominal Aortic Aneurysm
Masaharu Kobayashi, Katsuyuki Hoshina, Sota Yamamoto, Youkou Nemoto, Takafumi Akai, Kunihiro Shigematsu, Toshiaki Watanabe, Marie Ohshima

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1534

Assessment of In-Stent Restenosis Using High-Definition Computed Tomography With a New Gemstone Detector
Takuma Tsuda, Hideki Ishii, Satoshi Ichimiya, Masaaki Kanashiro, Jyunji Watanabe, Mikito Takefuji, Toru Aoyama, Susumu Suzuki, Akihito Tanaka, Tatsuaki Matsubara, Toyoaki Murohara

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1542

Diagnostic Performance of Artificial Neural Network for Detecting Ischemia in Myocardial Perfusion Imaging
Kenichi Nakajima, Shinro Matsuo, Hiroshi Wakabayashi, Kunihiko Yokoyama, Hisashi Bunko, Koichi Okuda, Seigo Kinuya, Karin Nyström, Lars Edenbrandt

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1549

Ischemic Heart Disease

Renal Nerve-Mediated Erythropoietin Release Confers Cardioprotection During Remote Ischemic Preconditioning
Toyoharu Oba, Hideo Yasukawa, Takanobu Nagata, Sachiko Kyogoku, Tomoko Minami, Michihide Nishihara, Hideki Ohshima, Kazutoshi Mawatari, Shoichiro Nohara, Jinya Takahashi, Yusuke Sugi, Sachiyo Igata, Yoshiko Iwamoto, Hisashi Kai, Hidehiro Matsuoka, Makoto Takano, Hiroki Aoki, Yoshihiro Fukumoto, Tsutomu Imaizumi

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1557

Effect of Abciximab Therapy in Patients Undergoing Coronary Angioplasty for Acute ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock
Francesco De Felice, Francesco Tomassini, Rosario Fiorilli, Andrea Gagnor, Antonio Parma, Enrico Cerrato, Carmine Musto, Marco Stefano Nazzaro, Ferdinando Varbella, Roberto Violini

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1568

Myocardial Disease

Visual Assessment of Relative Apical Sparing Pattern Is More Useful Than Quantitative Assessment for Diagnosing Cardiac Amyloidosis in Borderline or Mildly Increased Left Ventricular Wall Thickness
Ga Yeon Lee, Hyung-Kwan Kim, Jin-Oh Choi, Sung-A. Chang, Jae K. Oh, Eun-Seok Jeon, Dae-Won Sohn

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1575

Circulating CD14⁺⁺CD16⁺ Monocyte Subsets as a Surrogate Marker of the Therapeutic Effect of Corticosteroid Therapy in Patients With Cardiac Sarcoidosis
Makoto Orii, Toshio Imanishi, Ikuko Teraguchi, Tsuyoshi Nishiguchi, Yasutsugu Shiono, Takashi Yamano, Yasushi Ino, Kumiko Hirata, Takashi Kubo, Atsushi Tanaka, Takashi Akasaka

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1585

Effect of Corticosteroid Therapy on Long-Term Clinical Outcome and Left Ventricular Function in Patients With Cardiac Sarcoidosis
Toshiyuki Nagai, Nobutaka Nagano, Yasuo Sugano, Yasuhide Asaumi, Takeshi Aiba, Hideaki Kanzaki, Kengo Kusano, Teruo Noguchi, Satoshi Yasuda, Hisao Ogawa, Toshihisa Anzai

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1593

Association Between Basal Thinning of Interventricular Septum and Adverse Long-Term Clinical Outcomes in Patients With Cardiac Sarcoidosis
Nobutaka Nagano, Toshiyuki Nagai, Yasuo Sugano, Yoshiaki Morita, Yasuhide Asaumi, Takeshi Aiba, Hideaki Kanzaki, Kengo Kusano, Teruo Noguchi, Satoshi Yasuda, Hisao Ogawa, Toshihisa Anzai

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1601

Pediatric Cardiology and Adult Congenital Heart Disease

Comparison of 3 Risk Estimation Methods for Predicting Cardiac Outcomes in Pregnant Women With Congenital Heart Disease
Chun-Wei Lu, Jin-Chung Shih, Ssu-Yuan Chen, Hsin-Hui Chiu, Jou-Kou Wang, Chun-An Chen, Shuenn- Nan Chiu, Ming-Tai Lin, Chien-Nan Lee, Mei-Hwan Wu

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1609

Peripheral Vascular Disease

Poor Prognosis in Critical Limb Ischemia Without Pre-Onset Intermittent Claudication
Takuro Shirasu, Katsuyuki Hoshina, Satoshi Yamamoto, Kunihiro Shigematsu, Tetsuro Miyata, Toshiaki Watanabe

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1618

Renal Disease

Proteinuria and Reduced Estimated Glomerular Filtration Rate Are Independent Risk Factors for Contrast-Induced Nephropathy After Cardiac Catheterization
Yoshihiko Saito, Makoto Watanabe, Kazutaka Aonuma, Atsushi Hirayama, Nagara Tamaki, Hiroyuki Tsutsui, Toyoaki Murohara, Hisao Ogawa, Takashi Akasaka, Michihiro Yoshimura, Akira Sato, Tadateru Takayama, Mamoru Sakakibara, Susumu Suzuki, Kenichi Ishigami, Kenji Onoue on behalf of the CINC-J study investigators

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1624

Valvular Heart Disease

Comprehensive Risk Stratification of Japanese Patients With Aortic Stenosis – A Proposal of a New Risk Score From the CHART-2 Study –
Kenjiro Sato, Yasuhiko Sakata, Masanobu Miura, Soichiro Tadaki, Ryoichi Ushigome, Takeshi Yamauchi, Takeo Onose, Kanako Tsuji, Ruri Abe, Kotaro Nochioka, Jun Takahashi, Satoshi Miyata, Hiroaki Shimokawa on behalf of the CHART-2 Investigators

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1631

Images in Cardiovascular Medicine

Biatrial Myxomas With Various Manifestations – Carney Complex –
Yoichi Yamashita, Taiko Horii

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1639

Letters to the Editor

Assessment of the Anticoagulation Activity of Apixaban
(Letter) Luciana Ricca Gonçalves, Fernando Araújo

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1641

(Reply) Johanne Silvain

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Corrigendum

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1643

■月刊誌 Circulation Journal Vol.79 No.7 広告掲載企業様一覧
フォシーガ（アストラゼネカ株式会社）
クリアクター、コアテック、タンボコール、ニトロール、ワソラン（エーザイ株式会社）
英文翻訳校正サービス（カクタス・コミュニケーションズ株式会社）
リピディル（科研製薬株式会社）
グルベス（キッセイ薬品工業株式会社）
製品一覧（興和(株)）
ダイアート（株式会社三和化学研究所）
アイミクス（大日本住友製薬株式会社）
アジルバ、ザクラス（武田薬品工業株式会社）
メインテート（田辺三菱製薬株式会社）
H-FABP（DSファーマバイオメディカ）
ミカルディス　他（日本ベーリンガーインゲルハイム(株)）
VaSera、ＦＭ１９０（フクダ電子株式会社）
ドクターソフト（株式会社油井コンサルティング）
統合型統計パッケージ（株式会社ライトストーン）
（順不同）

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