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Message From the Editor-in-Chief

Message From the Editor-in-Chief
Hiroaki Shimokawa

Reviews

Mitochondrion as a Target for Heart Failure Therapy – Role of Protein Lysine Acetylation –
Chi Fung Lee, Rong Tian

Platelets: Small in Size But Essential in the Regulation of Vascular Homeostasis – Translation From Basic Science to Clinical Medicine –
Shinya Goto, Terumitsu Hasebe, Shu Takagi

Intestinal Immunity and Gut Microbiota as Therapeutic Targets for Preventing Atherosclerotic Cardiovascular Diseases
Tomoya Yamashita, Kazuyuki Kasahara, Takuo Emoto, Takuya Matsumoto, Taiji Mizoguchi, Naoki Kitano, Naoto Sasaki, Ken-ichi Hirata

Editorials

Do Two Eyes Really See More Than One? – Intravascular Ultrasound and Optical Coherence Tomography –
Shinjo Sonoda, Yutaka Otsuji

Differential Relationships Between Anemia and Outcome in Subgroups of Patients With Chronic Heart Failure
Yasuaki Nakagawa, Shinji Yasuno, Koichiro Kuwahara

Pulsatility During Left Ventricular Assist Device Treatment
Shunsuke Kawamoto, Yoshikatsu Saiki

Direct Transfer, Shorter Onset-to-Balloon Time, and Better Clinical Outcome in ST-Segment Elevation Myocardial Infarction
Takumi Higuma, Hiroyuki Hanada, Ken Okumura

How Can We Improve Prognosis in Patients With Acute Myocardial Infarction? – Lesson From Patients Without Primary Percutaneous Coronary Intervention –
Hideki Ishii, Toyoaki Murohara

Trans Fatty Acid and Coronary Artery Disease – Lessons From Seven Countries Study –
Hisashi Adachi

Is the Prevalence of Patent Foramen Ovale in Japanese Truly Low?
Kei Takahashi

The Future of Non-Invasive Angiogenic Therapy Using Acoustic Waves
Kenta Ito, Hiroaki Shimokawa

Can We Predict or Prevent Progression of Aortic Stenosis?
Masao Daimon

Roles of Canonical Transient Receptor Potential 6 in Basal [Ca²⁺]i Regulation in Pulmonary Venous Smooth Muscle Cells Under Chronic Hypoxia-Induced Hypertension
Takeo Itoh

Original Articles

Arrhythmia/Electrophysiology

Prospective Use of Microvolt T-Wave Alternans Testing to Guide Primary Prevention Implantable Cardioverter Defibrillator Therapy
Faisal M. Merchant, Jorge A. Salerno-Uriarte, Fabrizio Caravati, Stefania Falcone, Giulio Molon, Daniele Marangoni, Grzegorz Raczak, Ludmila Danilowicz-Szymanowicz, Roberto F. E. Pedretti, Simona Sarzi Braga, Takanori Ikeda, Leonardo Calo, Annamaria Martino, Demet Erciyes, Maurizio Piancastelli, Philippe Maury, Richard J. Cohen, Antonis A. Armoundas

Predictors and Proarrhythmic Consequences of Inappropriate Implantable Cardioverter-Defibrillator Therapy
Taro Tenma, Hisashi Yokoshiki, Kazuya Mizukami, Hirofumi Mitsuyama, Masaya Watanabe, Ryo Sasaki, Motoki Maeno, Yoshiro Matsui, Hiroyuki Tsutsui

Cardiovascular Intervention

Impact of Arterial Access Route on Bleeding Complications in Japanese Patients Undergoing Percutaneous Coronary Intervention – Insight From the PRASFIT Trial –
Shigeru Saito, Takaaki Isshiki, Takeshi Kimura, Hisao Ogawa, Hiroyoshi Yokoi, Masakatsu Nishikawa, Shunichi Miyazaki, Yuko Tanaka, Masato Nakamura on behalf of the PRASFIT-ACS and PRASFIT-Elective Investigators

Two-Year Clinical Outcomes of Newer-Generation Drug-Eluting Stent Implantation Following Rotational Atherectomy for Heavily Calcified Lesions
Hiroyuki Jinnouchi, Shoichi Kuramitsu, Tomohiro Shinozaki, Yohei Kobayashi, Takashi Hiromasa, Takashi Morinaga, Toru Mazaki, Kenichi Sakakura, Yoshimitsu Soga, Makoto Hyodo, Shinichi Shirai, Kenji Ando

Association of Intravascular Ultrasound- and Optical Coherence Tomography-Assessed Coronary Plaque Morphology With Periprocedural Myocardial Injury in Patients With Stable Angina Pectoris
Shigeki Kimura, Tomoyo Sugiyama, Keiichi Hishikari, Yosuke Yamakami, Yuichiro Sagawa, Keisuke Kojima, Hirofumi Ohtani, Hiroyuki Hikita, Atsushi Takahashi, Mitsuaki Isobe

Long-Term Clinical Outcomes of True and Non-True Bifurcation Lesions According to Medina Classification – Results From the COBIS (COronary BIfurcation Stent) II Registry –
Taek Kyu Park, Yong Hwan Park, Young Bin Song, Ju Hyeon Oh, Woo Jung Chun, Gu Hyun Kang, Woo Jin Jang, Joo-Yong Hahn, Jeong Hoon Yang, Seung-Hyuk Choi, Jin-Ho Choi, Sang Hoon Lee, Myung-Ho Jeong, Hyo-Soo Kim, Jae-Hwan Lee, Cheol Woong Yu, Seung Woon Rha, Yangsoo Jang, Jung Han Yoon, Seung-Jea Tahk, Ki Bae Seung, Jong-Seon Park, Hyeon-Cheol Gwon

Cardiovascular Surgery

Prophylactic Intra-Aortic Balloon Pump Before Ventricular Assist Device Implantation Reduces Perioperative Medical Expenses and Improves Postoperative Clinical Course in INTERMACS Profile 2 Patients
Teruhiko Imamura, Koichiro Kinugawa, Daisuke Nitta, Masaru Hatano, Osamu Kinoshita, Kan Nawata, Shunei Kyo, Minoru Ono

Perioperative Hypoalbuminemia Affects Improvement in Exercise Tolerance After Left Ventricular Assist Device Implantation
Teruhiko Imamura, Koichiro Kinugawa, Daisuke Nitta, Masaru Hatano, Osamu Kinoshita, Kan Nawata, Minoru Ono

Impact of Ross Operation on Outcome in Young Female Adult Patients Wanting to Have Children
Kazuki Morimoto, Takaya Hoashi, Koji Kagisaki, Jun Yoshimatsu, Isao Shiraishi, Hajime Ichikawa, Junjiro Kobayashi, Takeshi Nakatani, Toshikatsu Yagihara, Soichiro Kitamura, Tomoyuki Fujita

Heart Failure

Prognostic Impact of Anemia in Patients With Chronic Heart Failure – With Special Reference to Clinical Background: Report From the CHART-2 Study –
Takeshi Yamauchi, Yasuhiko Sakata, Tsuyoshi Takada, Kotaro Nochioka, Masanobu Miura, Soichiro Tadaki, Ryoichi Ushigome, Kenjiro Sato, Takeo Onose, Kanako Tsuji, Ruri Abe, Jun Takahashi, Satoshi Miyata, Hiroaki Shimokawa on behalf of the CHART-2 investigators

Advantage of Pulsatility in Left Ventricular Reverse Remodeling and Aortic Insufficiency Prevention During Left Ventricular Assist Device Treatment
Teruhiko Imamura, Koichiro Kinugawa, Daisuke Nitta, Masaru Hatano, Osamu Kinoshita, Kan Nawata, Minoru Ono

Ischemic Heart Disease

Prehospital Transfer Pathway and Mortality in Patients Undergoing Primary Percutaneous Coronary Intervention
Yoichi Imori, Takeshi Akasaka, Koki Shishido, Tomoki Ochiai, Kazuki Tobita, Futoshi Yamanaka, Shingo Mizuno, Shigeru Saito

Clinical Characteristics of Patients With Acute Myocardial Infarction Who Did Not Undergo Primary Percutaneous Coronary Intervention – Report From the MIYAGI-AMI Registry Study –
Kiyotaka Hao, Jun Takahashi, Kenta Ito, Satoshi Miyata, Taro Nihei, Kensuke Nishimiya, Ryuji Tsuburaya, Yasuharu Matsumoto, Yasuhiko Sakata, Satoshi Yasuda, Hiroaki Shimokawa on behalf of the MIYAGI-AMI Registry Study Investigators

Serum Trans-Fatty Acid Concentration Is Elevated in Young Patients With Coronary Artery Disease in Japan
Kenta Mori, Tatsuro Ishida, Tomoyuki Yasuda, Minoru Hasokawa, Tomoko Monguchi, Maki Sasaki, Kensuke Kondo, Hideto Nakajima, Masakazu Shinohara, Toshiro Shinke, Yasuhiro Irino, Ryuji Toh, Kunihiro Nishimura, Ken-ichi Hirata

Molecular Cardiology

A Common Mutation of Long QT Syndrome Type 1 in Japan
Hideki Itoh, Kenichi Dochi, Wataru Shimizu, Isabelle Denjoy, Seiko Ohno, Takeshi Aiba, Hiromi Kimura, Koichi Kato, Megumi Fukuyama, Kanae Hasagawa, Eric Schulze-Bahr, Pascale Guicheney, Minoru Horie

Pediatric Cardiology and Adult Congenital Heart Disease

Homocysteine and Arginine-to-Asymmetric Dimethylarginine Ratio Associated With Blood Pressure Abnormalities in Children With Early Chronic Kidney Disease
Shao-Ju Chien, I-Chun Lin, Chien-Ning Hsu, Mao-Hung Lo, You-Lin Tain

Prevalence of Patent Foramen Ovale in the Japanese Population – Autopsy Study –
Junko Kuramoto, Akio Kawamura, Tomohisa Dembo, Tokuhiro Kimura, Keiichi Fukuda, Yasunori Okada

Regenerative Medicine

Therapeutic Ultrasound Promotes Reperfusion and Angiogenesis in a Rat Model of Peripheral Arterial Disease
Babak Nazer, Farzin Ghahghaie, Risa Kashima, Tatiana Khokhlova, Camilo Perez, Lawrence Crum, Tom Matula, Akiko Hata

Valvular Heart Disease

Risk Factors for Progression of Degenerative Aortic Valve Disease in the Japanese – The Japanese Aortic Stenosis Study (JASS) Prospective Analysis –
Kazuhiro Yamamoto, Hideya Yamamoto, Masaaki Takeuchi, Akira Kisanuki, Takashi Akasaka, Nobuyuki Ohte, Yutaka Hirano, Kiyoshi Yoshida, Satoshi Nakatani, Yasuharu Takeda, Takashi Sozu, Tohru Masuyama

Vascular Biology and Vascular Medicine

Chronic Hypoxia Increases Intracellular Ca²⁺ Concentration via Enhanced Ca²⁺ Entry Through Receptor- Operated Ca²⁺ Channels in Pulmonary Venous Smooth Muscle Cells
Gongyong Peng, Shaoxing Li, Wei Hong, Jinxing Hu, Yongliang Jiang, Guoping Hu, Yimin Zou, Yumin Zhou, Juan Xu, Pixin Ran

Images in Cardiovascular Medicine

Time-Course Changes of Cardiac-Specific Inflammation in a Patient With Left Ventricular Calcified Amorphous Tumor
Hiroki Yasui, Hiroyuki Takahama, Hideaki Kanzaki, Hatsue Ishibashi-Ueda, Naomi Morita, Yasuo Sugano, Takuya Hasegawa, Takahiro Ohara, Makoto Amaki, Akira Funada, Yasushi Yoshikawa, Satoshi Yasuda, Hisao Ogawa, Toshihisa Anzai

Right Ventricular Wall Dissection With Ventricular Septal Rupture Following Myocardial Infarction Visualized on 3-Dimensional Transthoracic Echocardiography
Daihiko Hakuno, Sarasa Isobe, Nobuyuki Masaki, Takeshi Adachi

Letters to the Editor

Towards Safer Pregnancies in Women With Congenital Heart Disease
(Letter) Ali Balci, Jolien W. Roos-Hesselink, Petronella G. Pieper

(Reply) Chu-Wei Lu, Mei-Hwan Wu

■月刊誌 Circulation Journal Vol.79 No9 広告掲載企業様一覧
フォシーガ（アストラゼネカ株式会社）
クリアクター、コアテック、タンボコール、ニトロール、ワソラン（エーザイ株式会社）
リピディル（科研製薬株式会社）
グルベス（キッセイ薬品工業株式会社）
アイミクス（大日本住友製薬株式会社）
企業広告（武田薬品工業株式会社）
H-FABP（DSファーマバイオメディカ）
ミカルディス　他（日本ベーリンガーインゲルハイム(株)）
VaSera、ＦＭ１９０（フクダ電子株式会社）
エパデール（持田製薬株式会社）
ドクターソフト（株式会社油井コンサルティング）
統合型統計パッケージ（株式会社ライトストーン）
（順不同）

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