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Message From the Editor-in-Chief

Announcement of the 2018 JCS Meeting Activities (2)
Toyoaki Murohara

Reviews

After the Dawn - Balloon Pulmonary Angioplasty for Patients With Chronic Thromboembolic Pulmonary Hypertension -
Aiko Ogawa, Hiromi Matsubara

Long Non-Coding RNAs as Key Regulators of Cardiovascular Diseases
Koh Ono, Yasuhide Kuwabara, Takahiro Horie, Takeshi Kimura

Aging Modulates the Substrate and Triggers Remodeling in Atrial Fibrillation
Yung-Kuo Lin, Yi-Ann Chen, Ting-I Lee, Yao-Chang Chen, Shih-Ann Chen, Yi-Jen Chen

Editorials

Anticoagulation Therapy After Left Ventricular Assist Device Implantation
Yoshihisa Tanoue, Takeo Fujino, Akira Shiose

Cutting Edge Science and Medicine of Adenosine in Patients With Heart Failure
Hiroshi Asanuma, Masafumi Kitakaze

Is There Any Impact of ST Re-elevation on Patients With Acute Myocardial Infarction Following Reperfusion Therapy?
Kengo Tanabe

Should Measures of High-Density Lipoprotein Function Be Added to the Low-Density Lipoprotein Cholesterol Target Level-Based Guidelines for Prevention of Atherosclerotic Disease?
Ichiro Sakuma, Katsunori Ikewaki

Towards the Application of Endovascular Treatment for Superficial Femoral Artery
Atsubumi Murakami

Role of Tissue Factor in Vascular Failure
Teruo Inoue, Masashi Sakuma, Shigeru Toyoda, Koichi Node

Detrimental Effects of Insufficient Warfarin Therapy - A Warning Against Imprudent Use of Warfarin for Atrial Fibrillation Patients -
Junya Kuroda

Mesoangioblasts - A Newcomer in Cell-Based Treatment Strategy for Cardiovascular Disease? -
Ken-ichiro Sasaki, Yoshihiro Fukumoto

Late Breaking Cohort Studies (JCS 2018)

Anticoagulation Therapy for Venous Thromboembolism in the Real World - From the COMMAND VTE Registry -
Yugo Yamashita, Takeshi Morimoto, Hidewo Amano, Toru Takase, Seiichi Hiramori, Kitae Kim, Takashi Konishi, Masaharu Akao, Yohei Kobayashi, Takeshi Inoue, Maki Oi, Toshiaki Izumi, Kotaro Takahashi, Tomohisa Tada, Po-Min Chen, Koichiro Murata, Yoshiaki Tsuyuki, Hiroshi Sakai, Syunsuke Saga, Tomoki Sasa, Jiro Sakamoto, Chinatsu Yamada, Minako Kinoshita, Kiyonori Togi, Tomoyuki Ikeda, Katsuhisa Ishii, Kazuhisa Kaneda, Hiroshi Mabuchi, Hideo Otani, Kensuke Takabayashi, Mamoru Takahashi, Hiroki Shiomi, Takeru Makiyama, Koh Ono, Takeshi Kimura on behalf of COMMAND VTE Registry Investigators

Original Articles

Arrhythmia/Electrophysiology

Impact of B-Type Natriuretic Peptide Level on Risk Stratification of Thromboembolism and Death in Patients With Nonvalvular Atrial Fibrillation - The Hokuriku-Plus AF Registry -
Kenshi Hayashi, Toyonobu Tsuda, Akihiro Nomura, Noboru Fujino, Atsushi Nohara, Kenji Sakata, Tetsuo Konno, Chiaki Nakanishi, Hayato Tada, Yoji Nagata, Ryota Teramoto, Yoshihiro Tanaka, Masa-aki Kawashiri, Masakazu Yamagishi on behalf of the Hokuriku-Plus AF Registry Investigators

Aplastic Anemia and Risk of Incident Atrial Fibrillation - A Nationwide Cohort Study -
Wei-Syun Hu, Fung-Chang Sung, Cheng-Li Lin

Comparison of the 2MACE and TIMI-AF Scores for Composite Clinical Outcomes in Anticoagulated Atrial Fibrillation Patients
Daniele Pastori, José Miguel Rivera-Caravaca, María Asunción Esteve-Pastor, Vanessa Roldán, Francisco Marín, Pasquale Pignatelli, Francesco Violi, Gregory Y.H. Lip

Cardiovascular Intervention

Effect of Side Branch Predilation in Coronary Bifurcation Stenting With the Provisional Approach - Results From the COBIS (Coronary Bifurcation Stenting) II Registry -
Seung Hwa Lee, Young Bin Song, Joo Myung Lee, Taek Kyu Park, Jeong Hoon Yang, Joo-Yong Hahn, Jin-Ho Choi, Seung-Hyuk Choi, Sang Hoon Lee, Joong Hyun Ahn, Keumhee C. Carriere, Myung-Ho Jeong, Hyo-Soo Kim, Ju Hyeon Oh, Yangsoo Jang, Hyeon-Cheol Gwon

Epidemiology

“Ikigai”, Subjective Wellbeing, as a Modifier of the Parity-Cardiovascular Mortality Association - The Japan Collaborative Cohort Study -
Sumiyo Yasukawa, Eri Eguchi, Keiki Ogino, Akiko Tamakoshi, Hiroyasu Iso

Heart Failure

Survival of HeartMate II Patients Despite Cessation of Anticoagulation - Outcomes and Hemostatic Analysis -
Rashad Zayat, Mohammad Amen Khattab, Oliver Grottke, Markus Honickel, Andreas Goetzenich, Ajay Moza, Christian Stoppe, Rüdiger Autschbach, Lachmandath Tewarie

Endogenous Adenosine May Be Related to Left Ventricular Dysfunction, Dilation, and Wall Thinning in Patients With Heart Disease
Yujiro Kinomura, Toshiki Tanaka, Takuma Aoyama, Masanori Hatasa, Shingo Minatoguchi, Masamitsu Iwasa, Yoshihisa Yamada, Takahide Nawa, Hiromitsu Kanamori, Masanori Kawasaki, Yukihiro Esaka, Bunji Uno, Kazuhiko Nishigaki, Shinya Minatoguchi

Incidence and Risk Factors of Stroke or Systemic Embolism in Patients With Atrial Fibrillation and Heart Failure - The Fushimi AF Registry -
Moritake Iguchi, Yuji Tezuka, Hisashi Ogawa, Yasuhiro Hamatani, Daisuke Takagi, Yoshimori An, Takashi Unoki, Mitsuru Ishii, Nobutoyo Masunaga, Masahiro Esato, Hikari Tsuji, Hiromichi Wada, Koji Hasegawa, Mitsuru Abe, Gregory Y.H. Lip, Masaharu Akao

Nationwide Survey of Palliative Care for Patients With Heart Failure in Japan
Takashi Kuragaichi, Yuma Kurozumi, Shogo Ohishi, Yasuo Sugano, Akihiro Sakashita, Norihiko Kotooka, Makoto Suzuki, Taiki Higo, Dai Yumino, Yasuko Takada, Seiko Maeda, Saori Yamabe, Koichi Washida, Tomonori Takahashi, Tomohito Ohtani, Yasushi Sakata, Yukihito Sato

Novel Risk Score Efficiently Prevents Tolvaptan-Induced Hypernatremic Events in Patients With Heart Failure
Koichiro Kinugawa, Naoki Sato, Takayuki Inomata, Moriyoshi Yasuda, Yoshiyuki Shibasaki, Toshiyuki Shimakawa

Donor Polymorphisms in Genes Related to B-Cell Biology Associated With Antibody-Mediated Rejection After Heart Transplantation
Grecia M. Marrón-Liñares, Lucía Núñez, Mar ía G. Crespo-Leiro, Eloy Álvarez-López, Eduardo Barge-Caballero, Gonzalo Barge-Caballero, David Couto-Mallón, Concepción Pradas-Irun, Javier Muñiz, Carmela Tan, E. Rene Rodríguez, José Manuel Vázquez-Rodríguez, Manuel Hermida-Prieto

Imaging

Current Use of Intracoronary Imaging in Interventional Practice - Results of a European Association of Percutaneous Cardiovascular Interventions (EAPCI) and Japanese Association of Cardiovascular Interventions and Therapeutics (CVIT) Clinical Practice Survey -
Konstantinos C. Koskinas, Masato Nakamura, Lorenz Räber, Roisin Colleran, Kazushige Kadota, Davide Capodanno, William Wijns, Takashi Akasaka, Marco Valgimigli, Giulio Guagliumi, Stephan Windecker, Robert A. Byrne

Local Thickness of Epicardial Adipose Tissue Surrounding the Left Anterior Descending Artery Is a Simple Predictor of Coronary Artery Disease - New Prediction Model in Combination With Framingham Risk Score -
Gulinu Maimaituxun, Michio Shimabukuro, Daiju Fukuda, Shusuke Yagi, Yukina Hirata, Takashi Iwase, Shoichiro Takao, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masafumi Harada, Masataka Sata

Ischemic Heart Disease

Incidence and Significance of Spontaneous ST Segment Re-elevation After Reperfused Anterior Acute Myocardial Infarction - Relationship With Infarct Size, Adverse Remodeling, and Events at 1 Year -
Léo Cuenin, Sophie Lamoureux, Mathieu Schaaf, Thomas Bochaton, Jean-Pierre Monassier, Marc J. Claeys, Gilles Rioufol, Gérard Finet, David Garcia-Dorado, Denis Angoulvant, Meyer Elbaz, Nicolas Delarche, Pierre Coste, Marc Metge, Thibault Perret, Pascal Motreff, Eric Bonnefoy-Cudraz, Gérald Vanzetto, Olivier Morel, Inesse Boussaha, Michel Ovize, Nathan Mewton

Metabolic Disorder

Effect of Rosuvastatin on Cholesterol Efflux Capacity and Endothelial Function in Type 2 Diabetes Mellitus and Dyslipidemia
Kyong Yeun Jung, Kyoung Min Kim, Sun Kyoung Han, Han Mi Yun, Tae Jung Oh, Sung Hee Choi, Kyong Soo Park, Hak Chul Jang, Soo Lim

Molecular Cardiology

Apolipoprotein A-1 Binding Protein Inhibits Inflammatory Signaling Pathways by Binding to Apolipoprotein A-1 in THP-1 Macrophages
Min Zhang, Guo-Jun Zhao, Kai Yin, Xiao-Dan Xia, Duo Gong, Zhen-Wang Zhao, Ling-Yan Chen, Xi-Long Zheng, Xiao-Er Tang, Chao-Ke Tang

Myocardial Disease

Clinical Correlates and Prognostic Value of Elevated Right Atrial Pressure in Patients With Hypertrophic Cardiomyopathy
Stephen A. McCullough, Michael A. Fifer, Pouya Mohajer, Patricia A. Lowry, Caitlin O’Callaghan Reen, Aaron L. Baggish, Gus J. Vlahakes, Yuichi J. Shimada

Peripheral Vascular Disease

Impact of Stent-to-Vessel Diameter Ratio on Restenosis in the Superficial Femoral Artery After Endovascular Therapy
Naoya Kurata, Osamu Iida, Tatsuya Shiraki, Masashi Fujita, Masaharu Masuda, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takashi Kanda, Akihiro Sunaga, Takuya Tsujimura, Mitsuyoshi Takahara, Toshiaki Mano

Preventive Medicine

Effect of Smoking Status on Monocyte Tissue Factor Activity, Carotid Atherosclerosis and Long-Term Prognosis in Metabolic Syndrome
Keiichi Kohashi, Akihiro Nakagomi, Taichirou Morisawa, Ikuko Endoh, Naomi Kawaguchi, Yoshiki Kusama, Wataru Shimizu

Pulmonary Circulation

Long-Term Outcome of Chronic Thromboembolic Pulmonary Hypertension at a Single Japanese Pulmonary Endarterectomy Center
Hideki Miwa, Nobuhiro Tanabe, Takayuki Jujo, Fumiaki Kato, Rie Anazawa, Keiko Yamamoto, Akira Naito, Hajime Kasai, Rintaro Nishimura, Rika Suda, Toshihiko Sugiura, Seiichiro Sakao, Keiichi Ishida, Masahisa Masuda, Koichiro Tatsumi

Stroke

Insufficient Warfarin Therapy Is Associated With Higher Severity of Stroke Than No Anticoagulation in Patients With Atrial Fibrillation and Acute Anterior-Circulation Stroke
Yuki Sakamoto, Seiji Okubo, Chikako Nito, Satoshi Suda, Noriko Matsumoto, Yasuhiro Nishiyama, Junya Aoki, Takashi Shimoyama, Takuya Kanamaru, Kentaro Suzuki, Masahiro Mishina, Kazumi Kimura

Seasonal Variations in Neurological Severity and Outcomes of Ischemic Stroke - 5-Year Single- Center Observational Study -
Kazunori Toyoda, Masatoshi Koga, Hiroshi Yamagami, Chiaki Yokota, Shoichiro Sato, Manabu Inoue, Tomotaka Tanaka, Kaoru Endo, Jun Fujinami, Masafumi Ihara, Kazuyuki Nagatsuka, Kazuo Minematsu

Valvular Heart Disease

Prevalence and Prognostic Significance of Functional Mitral and Tricuspid Regurgitation Despite Preserved Left Ventricular Ejection Fraction in Atrial Fibrillation Patients
Yukio Abe, Kanako Akamatsu, Kazato Ito, Yoshiki Matsumura, Kenji Shimeno, Takahiko Naruko, Yosuke Takahashi, Toshihiko Shibata, Minoru Yoshiyama

Vascular Biology and Vascular Medicine

Heparin Induces the Mobilization of Heart-Derived Multipotent Mesoangioblasts During Cardiac Surgery With Cardiopulmonary Bypass or Cardiac Catheterization
Yoshihiro Hata, Masayoshi Iwasaki, Keisuke Fujitaka, Haengnam Park, Daisuke Sato, Chiharu Enoki, Naoki Minato, Keita Horitani, Miyuki Nakano, Hiroshi Kishimoto, Kensaku Wada, Masamichi Koyanagi, Yasushi Adachi, Yoshihiro Yamamoto, Andreas M. Zeiher, Stefanie Dimmeler, Ichiro Shiojima

Rapid Communications

Adiponectin in Chronic Thromboembolic Pulmonary Hypertension
Sarasa Isobe, Masaharu Kataoka, Takashi Kawakami, Keiichi Fukuda

Images in Cardiovascular Medicine

Huge Metastatic Gastrointestinal Stromal Tumor Occupying the Right Ventricle
Yudai Tamura, Hayato Tada, Hiroki Kato, Kenji Iino, Kenshi Hayashi, Masa-aki Kawashiri, Hirofumi Takemura, Masakazu Yamagishi

Exercise Ischemia Induced by Essential Thrombocytemia Diagnosed on Treadmill Test - Transcutaneous Oxygen Pressure Measurement of Foot Ischemia -
Loukman Omarjee, Olivier Stivalet, Guillaume Mahe, Vincent Jaquinandi

Severe Aortic and Mitral Stenosis Secondary to Slowly Progressive Hunter Syndrome in an Elderly Patient
Yosuke Takahashi, Takashi Murakami, Hiromichi Fujii, Masanori Sakaguchi, Shinsuke Nishimura, Daisuke Yasumizu, Yoshito Sakon, Yuki Kubo, Masahiko Osawa, Toshihiko Shibata

Perforation of the Left Atrial Appendage Caused by Inadvertent Deployment of a Soft J-Tipped Guidewire During Radiofrequency Hot-Balloon Ablation
Hiro Yamasaki, Fumi Yamagami, Takeshi Machino, Kenji Kuroki, Yukio Sekiguchi, Kazutaka Aonuma, Akihiko Nogami

Ventricular Fibrillation Due to Early Repolarization Syndrome in the Wake of Hypothermia Due to Fulminant Acute Disseminated Encephalomyelitis
Kyoichiro Yazaki, Yoichi Ajiro, Kunihiko Shimizu, Fumiaki Mori, Nobue Yagihara, Akinori Sato, Tatsuya Takahashi, Kazunori Iwade

■月刊誌 Circulation Journal Vol.82 No.5 広告掲載企業様一覧
フォシーガ（アストラゼネカ株式会社）
クリアクター、コアテック、タンボコール、ワソラン、ニトロール（エーザイ株式会社）
スイニー（株式会社三和化学研究所）
アイミクス（大日本住友製薬株式会社）
企業広告（武田薬品工業株式会社）
カナリア（田辺三菱製薬株式会社）
メインテート（田辺三菱製薬株式会社）
（順不同）

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