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Reviews

Emerging Role of Plasma Membranes in Vascular Endothelial Mechanosensing
Kimiko Yamamoto, Joji Ando

Editorials

Phenotype and Prognosis of the Lamin A/C Gene (LMNA) Mutation Carriers in Japan
Noboru Fujino, Kenshi Hayashi, Kenji Sakata, Akihiro Nomura, Masa-aki Kawashiri

Is Transesophageal Echocardiography Necessary in Every Case of Atrial Fibrillation Ablation?
Hideharu Okamatsu, Ken Okumura

Importance of Risk Control on the Incidence of Aortic Artery Disease-Related Disease in Epidemiological Studies
Hisashi Adachi

Alternative Exercise Intervention for Patients With Severe Peripheral Artery Disease — Akt1-Induced Blood Flow Recovery —
Kentaro Jujo, Nobuhisa Hagiwara

Original Articles

Arrhythmia/Electrophysiology

Clinical Manifestations and Long-Term Mortality in Lamin A/C Mutation Carriers From a Japanese Multicenter Registry
Kenzaburo Nakajima, Takeshi Aiba, Takeru Makiyama, Suguru Nishiuchi, Seiko Ohno, Koichi Kato, Yuta Yamamoto, Takahiro Doi, Satoshi Shizuta, Kenji Onoue, Nobue Yagihara, Taisuke Ishikawa, Ichiro Watanabe, Hiroshi Kawakami, Yasushi Oginosawa, Nobuyuki Murakoshi, Akihiko Nogami, Kazutaka Aonuma, Yoshihiko Saito, Takeshi Kimura, Satoshi Yasuda, Naomasa Makita, Wataru Shimizu, Minoru Horie, Kengo Kusano

Left Atrial Appendage Thrombus Prior to Atrial Fibrillation Ablation in the Era of Direct Oral Anticoagulants
Masahide Harada, Masayuki Koshikawa, Yuji Motoike, Tomohide Ichikawa, Kunihiko Sugimoto, Eiichi Watanabe, Yukio Ozaki

Ablation Index for Catheter Ablation of Atrial Fibrillation — Clinical Applicability and Comparison With Force-Time Integral —
Paula Münkler, Stefan Kröger, Spyridon Liosis, Amr Abdin, Evgeny Lyan, Charlotte Eitel, Ingo Eitel, Christian Meyer, Stephan Willems, Christian-Hendrik Heeger, Roland Richard Tilz

Uric Acid and Risk of Atrial Fibrillation in the Korean General Population
Chang Hee Kwon, Sung Ho Lee, Jong-Young Lee, Seungho Ryu, Ki-Chul Sung

Cardiovascular Intervention

Incidence and Clinical Course of Limb Dysfunction Post Cardiac Catheterization — A Systematic Review —
Muhammad Ayyaz Ul Haq, Muhammad Rashid, Ian C. Gilchrist, Olivier Bertrand, Chun Shing Kwok, Chun Wai Wong, Hossam M. Mansour, Yasser Baghdaddy, James Nolan, Maarten A.H. van Leeuwen, Mamas A. Mamas

Different Neointimal Pattern in Early vs. Late In-Stent Restenosis and Clinical Outcomes After Drug- Coated Balloon Angioplasty — An Optical Coherence Tomography Study —
Jung-Hee Lee, Hae Won Jung, Jung-Sun Kim, Sung-Jin Hong, Chul-Min Ahn, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang

Cardiac Rehabilitation

Impact of High Respiratory Exchange Ratio During Submaximal Exercise on Adverse Clinical Outcome in Heart Failure
Naoya Kakutani, Arata Fukushima, Takashi Yokota, Takashi Katayama, Hideo Nambu, Ryosuke Shirakawa, Satoshi Maekawa, Takahiro Abe, Shingo Takada, Takaaki Furihata, Kota Ono, Koichi Okita, Shintaro Kinugawa, Toshihisa Anzai

Cardiovascular Surgery

Robotic Transmitral Approach for Hypertrophic Cardiomyopathy With Systolic Anterior Motion
Nai-Kuan Chou, Ryoi Okano, Takeo Tedoriya, I-Hui Wu, Hsi-Yu Yu, Yih-Sharng Chen, Ming-Jiuh Wang, Nai-Hsin Chi

Trifecta vs. Magna for Aortic Valve Replacement — Differences in Clinical Outcome and Valve Hemodynamics —
Naoki Tadokoro, Satsuki Fukushima, Yusuke Shimahara, Yorihiko Matsumoto, Kizuku Yamashita, Naonori Kawamoto, Kimito Minami, Junjiro Kobayashi, Tomoyuki Fujita

Epidemiology

Effect of Hypertension on Aortic Artery Disease-Related Mortality — 3.8-Year Nationwide Community- Based Prospective Cohort Study —
Yoichiro Otaki, Tetsu Watanabe, Tsuneo Konta, Masafumi Watanabe, Shouichi Fujimoto, Yuji Sato, Koichi Asahi, Kunihiro Yamagata, Kazuhiko Tsuruya, Ichiei Narita, Masato Kasahara, Yugo Shibagaki, Kunitoshi Iseki, Toshiki Moriyama, Masahide Kondo, Tsuyoshi Watanabe

Heart Failure

LINC-PINT Activates the Mitogen-Activated Protein Kinase Pathway to Promote Acute Myocardial Infarction by Regulating miR-208a-3p
Jianzhong Zhu, Huimin Gu, Xiaolei Lv, Chunying Yuan, Ping Ni, Feng Liu

Prognostic Impact of the Preservation of Activities of Daily Living on Post-Discharge Outcomes in Patients With Acute Heart Failure
Yusuke Uemura, Rei Shibata, Kenji Takemoto, Masayoshi Koyasu, Shinji Ishikawa, Toyoaki Murohara, Masato Watarai

Transcatheter Repair of Functional Mitral Regurgitation in Heart Failure Patients — A Meta-Analysis of 23 Studies on MitraClip Implantation —
Roberta De Rosa, Angelo Silverio, Cesare Baldi, Marco Di Maio, Costantina Prota, Ilaria Radano, Julia Rey, Eva Herrmann, Rodolfo Citro, Federico Piscione, Gennaro Galasso

Demographics, Management, and In-Hospital Outcome of Hospitalized Acute Heart Failure Syndrome Patients in Contemporary Real Clinical Practice in Japan — Observations From the Prospective, Multicenter Kyoto Congestive Heart Failure (KCHF) Registry —
Hidenori Yaku, Neiko Ozasa, Takeshi Morimoto, Yasutaka Inuzuka, Yodo Tamaki, Erika Yamamoto, Yusuke Yoshikawa, Takeshi Kitai, Ryoji Taniguchi, Moritake Iguchi, Masashi Kato, Mamoru Takahashi, Toshikazu Jinnai, Tomoyuki Ikeda, Kazuya Nagao, Takafumi Kawai, Akihiro Komasa, Ryusuke Nishikawa, Yuichi Kawase, Takashi Morinaga, Kanae Su, Mitsunori Kawato, Kenichi Sasaki, Mamoru Toyofuku, Yutaka Furukawa, Yoshihisa Nakagawa, Kenji Ando, Kazushige Kadota, Satoshi Shizuta, Koh Ono, Yukihito Sato, Koichiro Kuwahara, Takao Kato, Takeshi Kimura on behalf of the KCHF Study Investigators

Imaging

Optical Coherence Tomography Predictors for Recurrent Restenosis After Paclitaxel-Coated Balloon Angioplasty for Drug-Eluting Stent Restenosis
Katsuya Miura, Takeshi Tada, Seiji Habara, Akimune Kuwayama, Takenobu Shimada, Masanobu Ohya, Ryosuke Murai, Hidewo Amano, Shunsuke Kubo, Suguru Otsuru, Hiroyuki Tanaka, Yasushi Fuku, Tsuyoshi Goto, Kazushige Kadota

Ischemic Heart Disease

Stimulation of the Beta2 Adrenergic Receptor at Reperfusion Limits Myocardial Reperfusion Injury via an Interleukin-10-Dependent Anti-Inflammatory Pathway in the Spleen
Yikui Tian, Bin Miao, Eric J. Charles, Di Wu, Irving L. Kron, Brent A. French, Zequan Yang

Diagnostic Performance of the Simultaneous Acquisition Rest ^{99 m}Tc-Tetrofosmin/Stress ²⁰¹Tl Dual-Isotope Protocol With a Semiconductor Camera — Comparison With the Rest-Stress ^{99 m}Tc- Tetrofosmin Protocol —
Itta Kawamura, Ryo Kajiura, Yusuke Motoji, Syuichi Okamoto, Toru Tanigaki, Hiroyuki Omori, Tetsuo Hirata, Jun Kikuchi, Hideaki Ota, Yoshihiro Sobue, Taiji Miyake, Tomohiro Tsunekawa, Takayoshi Kato, Yoshiaki Kawase, Munenori Okubo, Hiroki Kamiya, Kunihiko Tsuchiya, Shinji Tomita, Akihiro Hirakawa, Takeshi Kondo, Takahiko Suzuki, Hitoshi Matsuo

Number of Board-Certified Cardiologists and Acute Myocardial Infarction-Related Mortality in Japan — JROAD and JROAD-DPC Registry Analysis —
Koshiro Kanaoka, Satoshi Okayama, Kihei Yoneyama, Michikazu Nakai, Kunihiro Nishimura, Hiroyuki Kawata, Manabu Horii, Rika Kawakami, Hiroyuki Okura, Yoshihiro Miyamoto, Yoshihiro Akashi, Yoshihiko Saito

Significant Association Between Coronary Artery Low-Attenuation Plaque Volume and Apnea- Hypopnea Index, But Not Muscle Sympathetic Nerve Activity, in Patients With Obstructive Sleep Apnea Syndrome
Takuto Hamaoka, Hisayoshi Murai, Shuichi Kaneko, Soichiro Usui, Oto Inoue, Hiroyuki Sugimoto, Yusuke Mukai, Yoshitaka Okabe, Hideki Tokuhisa, Shinichiro Takashima, Takeshi Kato, Hiroshi Furusho, Soichiro Kashiwaya, Yu Sugiyama, Yasuto Nakatsumi, Shigeo Takata, Masayuki Takamura

Metabolic Disorder

MicroRNA-377 Inhibits Atherosclerosis by Regulating Triglyceride Metabolism Through the DNA Methyltransferase 1 in Apolipoprotein E-Knockout Mice
Ling-Yan Chen, Xiao-Dan Xia, Zhen-Wang Zhao, Duo Gong, Xiao-Feng Ma, Xiao-Hua Yu, Qiang Zhang, Si-Qi Wang, Xiao-Yan Dai, Xi-Long Zheng, Da-Wei Zhang, Wei-Dong Yin, Chao-Ke Tang

Stroke

Anti-Xa Activity and Event Risk in Patients With Direct Factor Xa Inhibitors Initiated Early After Stroke
Shinichi Wada, Kazunori Toyoda, Shoichiro Sato, Takayuki Matsuki, Takuya Okata, Masaya Kumamoto, Naoki Tagawa, Manabu Inoue, Akira Okamoto, Masafumi Ihara, Takanari Kitazono, Toshiyuki Miyata, Masatoshi Koga

Valvular Heart Disease

Discongruence Index — Simple Indicator to Predict Prosthesis-Patient Mismatch After Transcatheter Aortic Valve Replacement —
Jose Alberto de Agustin, Fabian Islas, Pilar Jimenez-Quevedo, Luis Nombela-Franco, Andrea Rueda Liñares, Patricia Mahia, Pedro Marcos-Alberca, Eduardo Pozo, Jose Juan Gomez de Diego, Maria Luaces, Ivan-Javier Nuñez-Gil, Miguel Ángel Garcia-Fernandez, Antonio Fernandez-Ortiz, Carlos Macaya, Leopoldo Perez de Isla

Surgical as Opposed to Transcatheter Aortic Valve Replacement Improves Basal Interventricular Septal Hypertrophy
Hidetoshi Yoshitani, Akihiro Isotani, Jae-Kwan Song, Shinichi Shirai, Hiromi Umeda, Jeong Yoon Jang, Takeshi Onoue, Misako Toki, Byung-Joo Sun, Dae-Hee Kim, Nobuyuki Kagiyama, Akihiro Hayashida, Jong-Min Song, Masataka Eto, Yosuke Nishimura, Kenji Ando, Michiya Hanyu, Kiyoshi Yoshida, Robert A. Levine, Yutaka Otsuji

Effect of the Initial Strategy for Active Endocarditis Complicated With Acute Heart Failure
Ryohei Matsuura, Daisuke Yoshioka, Koichi Toda, Junya Yokoyama, Shigeru Miyagawa, Yasushi Yoshikawa, Taichi Sakaguchi, Hiroyuki Nishi, Toshihiro Funatsu, Masao Yoshitatsu, Osamu Monta, Hirotsugu Fukuda, Yoshiki Sawa for the Osaka Cardiovascular Research (OSCAR) Study Group

Vascular Biology and Vascular Medicine

Akt1-Mediated Muscle Growth Promotes Blood Flow Recovery After Hindlimb Ischemia by Enhancing Heme Oxygenase-1 in Neighboring Cells
Yoshiro Onoue, Yasuhiro Izumiya, Shinsuke Hanatani, Toshifumi Ishida, Yuichiro Arima, Satoru Yamamura, Yuichi Kimura, Satoshi Araki, Masanobu Ishii, Taishi Nakamura, Yu Oimatsu, Kenji Sakamoto, Eiichiro Yamamoto, Sunao Kojima, Koichi Kaikita, Kenichi Tsujita

Rapid Communications

Use of Pulmonary Inhalants Remains Remarkably High After Atrial Septal Defect Closure
Martina Nassif, Odilia I. Woudstra, Joey M. Kuijpers, Peter J. Sterk, Reindert P. van Steenwijk, Aeilko H. Zwinderman, Berto J. Bouma, Barbara J. Mulder, Robbert J. de Winter

Images in Cardiovascular Medicine

Pathological Findings of Rivaroxaban-Associated Hemorrhagic Pericarditis
Masaki Kodaira, Hiroyuki Yamazaki, Ryota Tabei, Toshiki Kuno, Kazuhiko Shimizu, Yohei Numasawa

Primary Cardiac Diffuse Large B-Cell Lymphoma
Shu Yoshihara, Masaki Matsunaga, Fumihiko Tanioka, Masaaki Naito

Diastolic Tricuspid Regurgitation Related to Atrial Systole With a Bileaflet Mechanical Valve
Akihito Saito, Katsura Soma, Toshiya Kojima, Toshiro Inaba, Atsushi Yao, Issei Komuro

Impella 5.0 as a Bridge to Implantable Left Ventricular Assist Device — First Clinical Case in Japan —
Shohei Yoshida, Koichi Toda, Shigeru Miyagawa, Yasushi Yoshikawa, Hiroki Hata, Kei Torikai, Kazuo Shimamura, Shunsuke Saito, Keiwa Kin, Koichi Maeda, Keitaro Domae, Yoshiki Watanabe, Ryohei Matsuura, Kenta Masada, Shungo Hikoso, Isamu Mizote, Fusako Sera, Kei Nakamoto, Taito Masawa, Yasushi Sakata, Toru Kuratani, Yoshiki Sawa

Bidirectional Shunt Trajectory in Ventricular Septal Defect With Eisenmenger’s Syndrome
Hiromi Kayamori, Takeshi Kashimura, Yosuke Horii, Tsutomu Kanazawa, Toshio Fujita, Naoki Kubota, Yasuhiro Ikami, Toshiki Takano, Takeshi Okubo, Makoto Hoyano, Takao Yanagawa, Takuya Ozawa, Kazuyuki Ozaki, Tohru Minamino

Letters to the Editor

Bioresorbable Vascular Scaffolds: Is the Light Fading at the End of the Tunnel?
(Letter) Ahmed N. Mahmoud, Akram Y. Elgendy, Islam Y. Elgendy

(Reply) Jeehoon Kang, Hyo-Soo Kim

MitraClip in Patients With Severe Mitral Regurgitation and Severe Left Ventricular Systolic Dysfunction
(Letter) Ching-Wei Lee, Shih-Hsien Sung, Wei-Ming Huang, Chiao-Po Hsu, Kuo-Piao Chung

■月刊誌 Circulation Journal Vol.82 No.11 広告掲載企業様一覧
フォシーガ（アストラゼネカ株式会社）
クリアクター、コアテック、タンボコール、ワソラン、ニトロール（エーザイ株式会社）
ベルソムラ（МSD株式会社）
メトアナ（株式会社 三和化学研究所）
企業広告（武田薬品工業株式会社）
メインテート（田辺三菱製薬株式会社）
ドクターソフト（株式会社油井コンサルティングス）
（順不同）

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