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Reviews

The Future of Pharmacological Therapy for Heart Failure
Yusuke Sata, Henry Krum

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・809

Pleiotropic Effects of Statins
- Basic Research and Clinical Perspectives -
Qian Zhou, James K. Lia

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・818

Oxidative Stress and Central Cardiovascular Regulation
- Pathogenesis of Hypertension and Therapeutic Aspects -
Yoshitaka Hirooka, Yoji Sagara, Takuya Kishi, Kenji Sunagawa

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・827

Prostacyclin in Vascular Diseases
- Recent Insights and Future Perspectives -
Jun-ichi Kawabe, Fumitaka Ushikubi, Naoyuki Hasebe

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・836

Editorials

True Comparison of Different Stents in the Same Coronary Artery
Yasunori Ueda

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・844

Myocardial Transfection of Adeno-Hypoxia Inducible Factor-1α
- A Novel Strategy to Potentiate Vasculogenesis in Ischemic Myocardium -
Pavan Atluri

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・846

Should β-Blockers Be Prescribed More Frequently to Japanese Patients With Coronary Artery Disease?
Takuroh Imamura

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・848

Is a "Pharmacogenomic Algorithm" Helpful for Adjusting the Initial Dose of Warfarin in Patients to Be Treated by Warfarin Therapy?
Shinya Goto

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・850

True Autologous Approach in Cell Therapy
- Using Your Own Serum for Cell Culture -
Sung-Whan Kim, Young-Sup Yoon

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・852

Adventitia as a Critical Player in the Functional Integrity of Arteries
- Additional Support for Novel Clinical Procedures -
Siu Ling Wong, Yu Huang

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・854

Original Articles

Arrhythmia/Electrophysiology

Effects of Landiolol, an Ultra-Short-Acting β₁-Selective Blocker, on Electrical Storm Refractory to Class III Antiarrhythmic Drugs
Yosuke Miwa, Takanori Ikeda, Hisaaki Mera, Mutsumi Miyakoshi, Kyoko Hoshida, Ryoji Yanagisawa, Haruhisa Ishiguro, Takehiro Tsukada, Atsuko Abe, Satoru Yusu, Hideaki Yoshino

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・856

Efficacy of Procainamide and Lidocaine in Terminating Sustained Monomorphic Ventricular Tachycardia
- Retrospective Case Series -
Satoru Komura, Masaomi Chinushi, Hiroshi Furushima, Yukio Hosaka, Daisuke Izumi, Kenichi Iijima, Hiroshi Watanabe, Nobue Yagihara, Yoshifusa Aizawa

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・864

Impact of Drug Alteration to Maintain Rhythm Control in Paroxysmal Atrial Fibrillation
- Subanalysis From J-RHYTHM Study -
Ayaka Endo, Shun Kohsaka, Shinya Suzuki, Hirotsugu Atarashi, Shiro Kamakura, Masayuki Sakurai, Haruaki Nakaya, Masahiko Fukatani, Hideo Mitamura, Tsutomu Yamazaki, Takeshi Yamashita, Satoshi Ogawa, J-RHYTHM Investigators

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・870

Importance of Morphological Changes in T-U Waves During Bepridil Therapy as a Predictor of Ventricular Arrhythmic Event
Sayaka Kurokawa, Shinichi Niwano, Michiro Kiryu, Masami Murakami, Shoko Ishikawa, Yoshihiro Yumoto, Masahiko Moriguchi, Hiroe Niwano, Tomoko Kosukegawa, Tohru Izumi

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・876

Effect of Epicardial Fat Pad Ablation on Acute Atrial Electrical Remodeling and Inducibility of Atrial Fibrillation
Dong Chang, Shulong Zhang, Donghui Yang, Lianjun Gao, Yubi Lin, Zhenliang Chu, Xiaoxiao Jiang, Xiaomeng Yin, Zhitao Zheng, Xianjing Wei, Dejun You, Xianjie Xiao, Peixin Cong, Xiaoming Bian, Yunlong Xia, Yanzong Yang

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・885

Effect of Bepridil in Atrial Fibrillation Inducibility Facilitated by Vagal Nerve Stimulation
- Prevention of Vagal Nerve Activation-Induced Shortening of the Atrial Action Potential Duration -
Kenichi Iijima, Masaomi Chinushi, Daisuke Izumi, Shizue Ahara, Hiroshi Furushima, Satoru Komura, Yukio Hosaka, Akiko Sanada, Akinori Sato, Yoshifusa Aizawa

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・895

Cardiovascular Intervention

Comparison by Optical Coherence Tomography of Paclitaxel-Eluting Stents With Sirolimus-Eluting Stents Implanted in One Coronary Artery in One Procedure
- 6-Month Follow-up -
Naoki Miyoshi, Junya Shite, Toshiro Shinke, Hiromasa Otake, Yusuke Tanino, Daisuke Ogasawara, Takahiro Sawada, Hiroyuki Kawamori, Hiroki Kato, Naoki Yoshino, Amane Kozuki, Ken-ichi Hirata

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・903

High Index of Microcirculatory Resistance Level After Successful Primary Percutaneous Coronary Intervention Can Be Improved by Intracoronary Administration of Nicorandil
Noritoshi Ito, Shinsuke Nanto, Yasuji Doi, Hirotaka Sawano, Daisaku Masuda, Shizuya Yamashita, Ken-ichiro Okada, Shoji Kaibe, Yasuyuki Hayashi, Tatsuro Kai, Toru Hayashi

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・909

Cardiovascular Surgery

Myocardial Transfection of Hypoxia Inducible Factor-1α via an Adenoviral Vector During Coronary Artery Bypass Grafting
- A Multicenter Phase I and Safety Study -
Eckehard Gerd Kilian, Sebastian Sadoni, Calin Vicol, Ralph Kelly, Karen van Hulst, Markus Schwaiger, Christian Kupatt, Peter Boekstegers, Ravi Pillai, Keith Channon, Roland Hetzer, Bruno Reichart

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・916

Outcomes Following Use of a Modified Duran Ring Tricuspid Valve Reconstruction Procedure for Secondary Tricuspid Regurgitation
Sung-Ho Jung, Hyung Gon Je, Jong Min Song, Suk Jung Choo, Cheol Hyun Chung, Sung Cheol Yun, Jae Won Lee

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・925

Epidemiology

Associations Between Lipid Measures and Metabolic Syndrome, Insulin Resistance and Adiponectin
- Usefulness of Lipid Ratios in Korean Men and Women -
Heejin Kimm, Sang Wha Lee, Hong Soo Lee, Kyung Won Shim, Choo Yon Cho, Ji Eun Yun, Sun Ha Jee

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・931

Hypertension and Circulatory Control

Impact of Electrocardiographic Left Ventricular Hypertrophy on the Occurrence of Cardiovascular Events in Elderly Hypertensive Patients
- The Japanese Trial to Assess Optimal Systolic Blood Pressure in Elderly Hypertensive Patients (JATOS) -
Satoshi Jissho, Kenei Shimada, Haruyuki Taguchi, Ken Yoshida, Shota Fukuda, Hidemasa Tanaka, Junichi Yoshikawa, Minoru Yoshiyama, Masao Ishii, Yoshio Goto

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・938

Imaging

Evaluation of Cardiac Allograft Vasculopathy by Multidetector Computed Tomography and Whole-Heart Magnetic Resonance Coronary Angiography
Shinichi Nunoda, Haruhiko Machida, Akihiko Sekikawa, Kazunobu Shitakura, Kiyotaka Okajima, Yutaka Kubo, Eiko Ueno, Kuniaki Otsuka

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・946

Ischemic Heart Disease

Coronary Plaque Regression and Lifestyle Modification in Patients Treated With Pravastatin
- Assessment Mainly by Daily Aerobic Exercise and an Increase in the Serum Level of High-Density Lipoprotein Cholesterol -
Shigemasa Tani, Ken Nagao, Takeo Anazawa, Hirofumi Kawamata, Shingo Furuya, Hiroshi Takahashi, Kiyoshi Iida, Michiaki Matsumoto, Takehiko Washio, Narimichi Kumabe, Atsushi Hirayama

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・954

Beta-Blocker Prescription Among Japanese Cardiologists and Its Effect on Various Outcomes
Takahide Kohro, Dobun Hayashi, Tsutomu Yamazaki, Ryozo Nagai, The JCAD Investigators

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・962

Periodic Variation and Its Effect on Management and Prognosis of Korean Patients With Acute Myocardial Infarction
Hyo Eun Park, Bon-Kwon Koo, Wonjae Lee, Youngjin Cho, Jin Sik Park, Ji-Yong Choi, Myung-Ho Jeong, Jong Hyun Kim, Shung Chull Chae, Young Jo Kim, Chang-Wook Nam, Jae-Hwan Lee, Dong Hoon Choi, Taek Jong Hong, Jei Keon Chae, Jae Young Rhew, Kee Sik Kim, Hyo-Soo Kim, Byung-Hee Oh, Young Bae Park for KAMIR investigators

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・970

Molecular Cardiology

Evaluation of Pharmacogenetic Algorithm for Warfarin Dose Requirements in Japanese Patients
Fumihiko Takeuchi, Mitsuo Kashida, Osamu Okazaki, Yuriko Tanaka, Shoji Fukuda, Toshitaka Kashima, Shigeru Hosaka, Michiaki Hiroe, Sosuke Kimura, Norihiro Kato

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・977

IL-10 Polymorphisms Are Associated With Coronary Artery Lesions in Acute Stage of Kawasaki Disease
Ken-Pen Weng, Kai-Sheng Hsieh, Yu-Tung Hwang, Shih-Hui Huang, Tsung-Jen Lai, Yeong-Seng Yuh, Yu-Yi Hou, Chu-Chuan Lin, Shih-Chen Huang, Chian-Kai Chang, Ming-Wei Lin, Luo-Ping Ger

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・983

Genetic Analysis of Young Adult Patients With Aortic Disease Not Fulfilling the Diagnostic Criteria for Marfan Syndrome
Koichi Akutsu, Hiroko Morisaki, Toshiya Okajima, Tsuyoshi Yoshimuta, Yoshiaki Tsutsumi, Satoshi Takeshita, Hiroshi Nonogi, Hitoshi Ogino, Masahiro Higashi, Takayuki Morisaki

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・990

Pediatric Cardiology and Adult Congenital Heart Disease

The Role of N-Terminal Pro-B-Type Natriuretic Peptide in the Diagnosis of Congestive Heart Failure in Children
- Correlation With the Heart Failure Score and Comparison With B-Type Natriuretic Peptide -
Masaya Sugimoto, Hiromi Manabe, Kouichi Nakau, Akiko Furuya, Kasumi Okushima, Hiroaki Fujiyasu, Fujio Kakuya, Kazutomo Goh, Kenji Fujieda, Hiroki Kajino

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・998

Regenerative Medicine

Evidence for the Therapeutic Potential of Ex Vivo Expanded Human Endothelial Progenitor Cells Using Autologous Serum
Takanori Shumiya, Rei Shibata, Yuuki Shimizu, Masakazu Ishii, Ryuji Kubota, Satoshi Shintani, Toyoaki Murohara

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1006

Vascular Medicine

Effects of Removing the Adventitia on the Mechanical Properties of Ovine Femoral Arteries In Vivo and In Vitro
Edmundo Cabrera Fischer, Daniel Bia Santana, Yanina Zócalo, Juan Camus, Eduardo de Forteza, Ricardo Armentano

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1014

Rapid Communication

Vascular Response to Overlapping Everolimus-Eluting Stents
- Comparison With Paclitaxel-Eluting Stents -
Hiromasa Otake, Yasuhiro Honda, Masao Yamasaki, Ichizo Tsujino, Takao Shimohama, Ryota Sakurai, Takao Hasegawa, Katsuhisa Waseda, Junya Ako, Peter J. Fitzgerald

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1023

Images in Cardiovascular Medicine

Assessment of a Coronary Artery Fistula Using Coronary Pressure Wire
Olivier Muller, Sofie Verstreken, Marc Vanderheyden

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1026

Letters to the Editor

Invasive or Non-Iinvasive? That Is (Still) the Question
Alessandro Desideri

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1028

Author's Reply

Invasive or Non-Invasive? That Is (Still) the Question
- Reply -
Masahiro Yasutake, Teruo Takano

・・・・・・・・・・・・・・・・・・・・・・・・・・・・・・1029

■月刊誌 Circulation Journal Vol.74 No.5 広告掲載企業様一覧
プロサイリン、リピディル（科研製薬株式会社）
グルファスト（キッセイ薬品工業株式会社）
リバロ（興和創薬株式会社）
アマリール（サノフィ・アベンティス株式会社）
セイブル（株式会社 三和化学研究所）
レザルタス（第一三共株式会社）
アバプロ（大日本住友製薬株式会社）
ブロプレス、エカード（武田薬品工業株式会社）
シグマート（中外製薬株式会社）
アイトロール、フランドル、ミオコール、プロノン、シベノール（トーアエイヨー株式会社）
ミリスロール、ミリステープ（日本化薬株式会社）
ミカルディス、ミコンビ（日本ベーリンガーインゲルハイム株式会社）
Endeavor（日本メドトロニック株式会社）
アダラートCR（バイエル薬品株式会社）
グルコバイ（バイエル薬品株式会社）
プレミネント（万有製薬株式会社）
Preirus（株式会社日立メディコ）
ノルバスク、セララ（ファイザー株式会社）
VS-1500E、FM190（フクダ電子株式会社）
（順不同）

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