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Laboratory Introduction:A progressive chain of pathophysiological events links cardiovascular risk factors to clinical manifestations of disease and life-threatening cardiovascular events. This chain--the cardiovascular continuum--underlies cardiovascular disease and holds the key to its prevention and treatment. Pre-emptive medicine is a novel medical concept that aims to precisely assess tailored cardiovascular risk and disease management in individual patients. Recent advances in genomic analysis, information technology, and artificial intelligence should make this medical concept feasible. The research policy of our department is to conduct translational research, ranging from basic science to clinical research with high originality to deliver precision or preemptive medicine.
Recent Publications
・Yasuda S, et al. Antithrombotic Therapy for Atrial Fibrillation with Stable Coronary Disease. NEngl J Med. 2019 Sep 19;381(12):1103-1113. doi: 10.1056/NEJMoa1904143. Epub 2019 Sep 2. PMID: 31475793.
・Nakashima T, Yasuda S, et al. Public-access defibrillation and neurological outcomes in patients with out-of-hospital cardiac arrest in Japan:a population-based cohort study. Lancet. 2019 Dec 21;394(10216):2255-2262. doi:10.1016/S0140-6736(19)32488-2. Epub 2019 Dec 17. PMID: 31862250.
・Brieger D, Yasuda S, et al.Two-year outcomes among stable high-risk patients following acute MI. Insights from a global registry in 25 countries. Int J Cardiol. 2020 Jul 15;311:7-14. doi: 10.1016/j.ijcard.2020.01.070. Epub 2020 Jan 28. PMID: 32057476.
・Tern PJW, Yasuda S, et al. Comparative Overview of ST-Elevation Myocardial Infarction (STEMI) Epidemiology, Demographics, Management and Outcomes in 5 Asia-Pacific Countries - A Meta-Analysis. Eur Heart J Qual Care Clin Outcomes.2020 Jun 25:qcaa057. doi: 10.1093/ehjqcco/qcaa057. Epub ahead of print. PMID:32584986. |